Extracellular vesicles in myeloid neoplasms

C Karantanou, VR Minciacchi… - International journal of …, 2022 - mdpi.com
Myeloid neoplasms arise from malignant primitive cells, which exhibit growth advantage
within the bone marrow microenvironment (BMM). The interaction between these malignant …

Deepening Our Understanding of the Factors Affecting Landscape of Myeloproliferative Neoplasms: What Do We Know about Them?

ML Morales, F Ferrer-Marín - Cancers, 2023 - mdpi.com
Simple Summary Since the discovery of the role of the three driver mutations (JAK2, CALR
and MPL) and the constitutive activation of the JAK/STAT pathway in myeloproliferative …

Fecal microbial community composition in myeloproliferative neoplasm patients is associated with an inflammatory state

A Oliver, K El Alaoui, C Haunschild… - Microbiology …, 2022 - Am Soc Microbiol
The capacity of the human microbiome to modulate inflammation in the context of cancer is
becoming increasingly clear. Myeloproliferative neoplasms (MPNs) are chronic hematologic …

Pronounced gut microbiota signatures in patients with JAK2V617F-positive essential thrombocythemia

CS Eickhardt-Dalbøge, AC Ingham… - Microbiology …, 2023 - Am Soc Microbiol
Essential thrombocythemia (ET) is part of the Philadelphia chromosome-negative
myeloproliferative neoplasms. It is characterized by an increased risk of thromboembolic …

JAK2V617F drives gut microbiota differences in patients with myeloproliferative neoplasms

CS Eickhardt‐Dalbøge, HV Nielsen… - European Journal of …, 2024 - Wiley Online Library
Background Essential thrombocythemia (ET), polycythemia vera (PV), and primary
myelofibrosis (MF) are myeloproliferative neoplasms (MPN). Inflammation is involved in the …

Assessment of intestinal status in MPLW515L mutant myeloproliferative neoplasms mice model

S Zhu, K Xu, S Li, X Yu, Y Liu, Q Zhang, L Zeng… - International …, 2023 - Elsevier
Abstract The MPL W515L mutation is a prevalent genetic mutation in patients with
myeloproliferative neoplasms (MPN), and utilizing this mutation in mice model can provide …

The gut microbiota in patients with polycythemia vera is distinct from that of healthy controls and varies by treatment

CS Eickhardt-Dalbøge, AC Ingham… - Blood …, 2023 - ashpublications.org
Chronic inflammation is believed to play an important role in the development and disease
progression of polycythemia vera (PV). Because an association between gut microbiota …

Gut microbiota and myeloproliferative neoplams

AA Adesola, Y Chen… - JPMA. The Journal of …, 2023 - pubmed.ncbi.nlm.nih.gov
Gut microbiota and myeloproliferative neoplams Gut microbiota and myeloproliferative neoplams
J Pak Med Assoc. 2023 Dec;73(12):2334-2336. doi: 10.47391/JPMA.23-99. Authors Adeniyi …