The toxicogenomic multiverse: convergent recruitment of proteins into animal venoms

BG Fry, K Roelants, DE Champagne… - Annual review of …, 2009 - annualreviews.org
Throughout evolution, numerous proteins have been convergently recruited into the venoms
of various animals, including centipedes, cephalopods, cone snails, fish, insects (several …

[HTML][HTML] The role of saliva in tick feeding

IMB Francischetti, A Sa-Nunes, BJ Mans… - … in bioscience: a …, 2009 - ncbi.nlm.nih.gov
When attempting to feed on their hosts, ticks face the problem of host hemostasis (the
vertebrate mechanisms that prevent blood loss), inflammation (that can produce itching or …

Argasid and ixodid systematics: implications for soft tick evolution and systematics, with a new argasid species list

BJ Mans, J Featherston, M Kvas, KA Pillay… - Ticks and tick-borne …, 2019 - Elsevier
The systematics of the genera and subgenera within the soft tick family Argasidae is not
adequately resolved. Different classification schemes, reflecting diverse schools of scientific …

New insights into the machinery of blood digestion by ticks

D Sojka, Z Franta, M Horn, CR Caffrey, M Mareš… - Trends in …, 2013 - cell.com
Blood-protein digestion is a key physiological process providing essential nutrients for ticks
and is a prerequisite for the transmission of tick-borne pathogens. Recently, substantial …

Proteomic Analysis of Cattle Tick Rhipicephalus (Boophilus) microplus Saliva: A Comparison between Partially and Fully Engorged Females

L Tirloni, J Reck, RMS Terra, JR Martins, A Mulenga… - PloS one, 2014 - journals.plos.org
The cattle tick Rhipicephalus (Boophilus) microplus is one of the most harmful parasites
affecting bovines. Similarly to other hematophagous ectoparasites, R. microplus saliva …

Hemoglobin digestion in blood-feeding ticks: mapping a multipeptidase pathway by functional proteomics

M Horn, M Nussbaumerová, M Šanda, Z Kovářová… - Chemistry & biology, 2009 - cell.com
Hemoglobin digestion is an essential process for blood-feeding parasites. Using chemical
tools, we deconvoluted the intracellular hemoglobinolytic cascade in the tick Ixodes ricinus …

Protease inhibitors in tick saliva: the role of serpins and cystatins in tick-host-pathogen interaction

J Chmelař, J Kotál, H Langhansová… - Frontiers in cellular and …, 2017 - frontiersin.org
The publication of the first tick sialome (salivary gland transcriptome) heralded a new era of
research of tick protease inhibitors, which represent important constituents of the proteins …

TickSialoFam (TSFam): a database that helps to classify tick salivary proteins, a review on tick salivary protein function and evolution, with considerations on the tick …

JMC Ribeiro, BJ Mans - Frontiers in cellular and infection microbiology, 2020 - frontiersin.org
Tick saliva contains a complex mixture of peptides and non-peptides that counteract their
hosts' hemostasis, immunity, and tissue-repair reactions. Recent transcriptomic studies have …

Acquisition of exogenous haem is essential for tick reproduction

J Perner, R Sobotka, R Sima, J Konvickova, D Sojka… - Elife, 2016 - elifesciences.org
Haem and iron homeostasis in most eukaryotic cells is based on a balanced flux between
haem biosynthesis and haem oxygenase-mediated degradation. Unlike most eukaryotes …

RNA-seq analyses of the midgut from blood- and serum-fed Ixodes ricinus ticks

J Perner, J Provazník, J Schrenková, V Urbanová… - Scientific reports, 2016 - nature.com
Adult females of the genus Ixodes imbibe blood meals exceeding about 100 times their own
weight within 7‒9 days. During this period, ticks internalise components of host blood by …