[HTML][HTML] Clostridium difficile and one health

SC Lim, DR Knight, TV Riley - Clinical Microbiology and Infection, 2020 - Elsevier
Background For over four decades, Clostridium difficile has been a significant enteric
pathogen of humans. It is associated with the use of antimicrobials that generally disrupt the …

[HTML][HTML] Infection prevention and control insights from a decade of pathogen whole-genome sequencing

DW Eyre - Journal of Hospital Infection, 2022 - Elsevier
Pathogen whole-genome sequencing has become an important tool for understanding the
transmission and epidemiology of infectious diseases. It has improved our understanding of …

Development and Implementation of Whole Genome Sequencing-Based Typing Schemes for Clostridioides difficile

S Janezic, M Rupnik - Frontiers in Public Health, 2019 - frontiersin.org
Clostridioides difficile is an important nosocomial pathogen increasingly observed in the
community and in different non-human reservoirs. The epidemiology and transmissibility of …

Health care environmental hygiene: new insights and centers for disease control and prevention guidance

PC Carling - Infectious Disease Clinics, 2021 - id.theclinics.com
As a result of epidemiologic and microbiologic studies over the past decade, it has become
increasingly evident that interventions to mitigate environmental surface pathogen …

[HTML][HTML] Emerging Diagnostics in Clostridioides difficile Infection

JP Hulme - International Journal of Molecular Sciences, 2024 - mdpi.com
Clostridioides difficile detection in community settings is time-intensive, resulting in delays in
diagnosing and quarantining infected individuals. However, with the advent of semi …

Neutralising Effects of Different Antibodies on Clostridioides difficile Toxins TcdA and TcdB in a Translational Approach

G Csukovich, N Kramer, B Pratscher, I Gotic… - International Journal of …, 2023 - mdpi.com
Given the high prevalence of intestinal disease in humans and animals, there is a strong
need for clinically relevant models recapitulating gastrointestinal systems, ideally replacing …

Environmental approaches to controlling Clostridioides difficile infection in healthcare settings

PC Carling, MF Parry, R Olmstead - Antimicrobial Resistance & Infection …, 2023 - Springer
As today's most prevalent and costly healthcare-associated infection, hospital-onset
Clostridioides difficile infection (HO-CDI) represents a major threat to patient safety world …

Clostridium difficile in soil conditioners, mulches and garden mixes with evidence of a clonal relationship with historical food and clinical isolates

SC Lim, DR Knight, P Moono… - Environmental …, 2020 - Wiley Online Library
With rates of community‐associated Clostridium difficile infection (CA‐CDI) increasing
worldwide, potential reservoirs/sources of C. difficile in the community are being sought …

Comparative genomic and transmission analysis of Clostridioides difficile between environmental, animal, and clinical sources in China

Y Zhou, W Zhou, T Xiao, Y Chen, T Lv… - Emerging Microbes & …, 2021 - Taylor & Francis
Clostridioides difficile is the most common pathogen causing antibiotic-associated diarrhea.
Previous studies showed that diverse sources, aside from C. difficile infection (CDI) patients …

Whole genome sequencing for surveillance of diphtheria in low incidence settings

HMB Seth-Smith, A Egli - Frontiers in public health, 2019 - frontiersin.org
Corynebacterium diphtheriae (C. diphtheriae) is a relatively rare pathogen in most Western
countries. While toxin producing strains can cause pharyngeal diphtheria with potentially …