Review of the amphibian immune response to chytridiomycosis, and future directions
The fungal skin disease, chytridiomycosis (caused by Batrachochytrium dendrobatidis and
B. salamandrivorans), has caused amphibian declines and extinctions globally since its …
B. salamandrivorans), has caused amphibian declines and extinctions globally since its …
Virulence and pathogenicity of chytrid fungi causing amphibian extinctions
Ancient enzootic associations between wildlife and their infections allow evolution to
innovate mechanisms of pathogenicity that are counterbalanced by host responses …
innovate mechanisms of pathogenicity that are counterbalanced by host responses …
Transcriptome mining extends the host range of the Flaviviridae to non-bilaterians
The flavivirids (family Flaviviridae) are a group of positive-sense RNA viruses that include
well-documented agents of human disease. Despite their importance and ubiquity, the …
well-documented agents of human disease. Despite their importance and ubiquity, the …
Understanding the evolution of immune genes in jawed vertebrates
Driven by co‐evolution with pathogens, host immunity continuously adapts to optimize
defence against pathogens within a given environment. Recent advances in genetics …
defence against pathogens within a given environment. Recent advances in genetics …
Mining amphibian and insect transcriptomes for antimicrobial peptide sequences with rAMPage
Antibiotic resistance is a global health crisis increasing in prevalence every day. To combat
this crisis, alternative antimicrobial therapeutics are urgently needed. Antimicrobial peptides …
this crisis, alternative antimicrobial therapeutics are urgently needed. Antimicrobial peptides …
Immunological aspects of chytridiomycosis
Amphibians are currently the most threatened vertebrate class, with the disease
chytridiomycosis being a major contributor to their global declines. Chytridiomycosis is a …
chytridiomycosis being a major contributor to their global declines. Chytridiomycosis is a …
Sustained immune activation is associated with susceptibility to the amphibian chytrid fungus
AE Savage, B Gratwicke, K Hope… - Molecular …, 2020 - Wiley Online Library
The disease chytridiomycosis caused by the fungus Bd has devastated amphibian
populations worldwide. Functional genomic contributions to host susceptibility remain …
populations worldwide. Functional genomic contributions to host susceptibility remain …
Incapacitating effects of fungal coinfection in a novel pathogen system
As globalization lowers geographic barriers to movement, coinfection with novel and
enzootic pathogens is increasingly likely. Novel and enzootic pathogens can interact …
enzootic pathogens is increasingly likely. Novel and enzootic pathogens can interact …
Panzootic chytrid fungus exploits diverse amphibian host environments through plastic infection strategies
M Torres‐Sánchez, J Villate… - Molecular …, 2022 - Wiley Online Library
While some pathogens are limited to single species, others can colonize many hosts, likely
contributing to the emergence of novel disease outbreaks. Despite this biodiversity threat …
contributing to the emergence of novel disease outbreaks. Despite this biodiversity threat …
Towards a more healthy conservation paradigm: integrating disease and molecular ecology to aid biological conservation†
Parasites, and the diseases they cause, are important from an ecological and evolutionary
perspective because they can negatively affect host fitness and can regulate host …
perspective because they can negatively affect host fitness and can regulate host …