Objectives: Major depressive disorder (MDD) is one of the most disabling mental illnesses
and it has a significant impact on society. This review aims to provide updated scientific …

Depression is a highly prevalent risk factor for incident coronary heart disease (CHD) and for
cardiovascular morbidity and mortality in patients with established CHD. Several biological …

874 Circulation September 1, 2015 references are intended to be illustrative and to highlight
significant knowledge in the field. The premise underlying this scientific statement is that, at …

Major depression disorder (MDD) is a debilitating mental illness with significant morbidity
and mortality. Despite the growing number of studies that have emerged, the precise …

Background—Although prospective studies, systematic reviews, and meta-analyses have
documented an association between depression and increased morbidity and mortality in a …

Epidemiological data are reviewed on the prevalence, course, socio-demographic
correlates, and societal costs of major depression throughout the world. Major depression is …

Importance Depression is associated with increased disease burden worldwide and with
higher risk of mortality in Western populations. Objective To investigate whether depression …

Objective Several hundred studies have shown that depression is associated with an
elevated risk of dying at follow-up. It is not clear, however, whether the mechanisms for this …

Background Coronary heart disease (CHD) is the most common cause of death globally,
although mortality rates are falling. Psychological symptoms are prevalent for people with …

Major depression is a commonly occurring, seriously impairing, and often recurrent mental
disorder. 1, 2 The World Health Organization (WHO) ranks major depressive disorder (MDD) …