Vascular inflammation in hypertension: targeting lipid mediators unbalance and nitrosative stress

AS Bruno, PD Lopes, K de Oliveira… - Current …, 2021 - ingentaconnect.com
Arterial hypertension is a worldwide public health threat. High Blood Pressure (BP) is
commonly associated with endothelial dysfunction, nitric oxide synthases (NOS) unbalance …

Plasma Biomarkers for Hypertension-Mediated Organ Damage Detection: A Narrative Review

X Liu, M Yang, GYH Lip, G McDowell - Biomedicines, 2024 - mdpi.com
Hypertension (HT) is a disease that poses a serious threat to human health, mediating organ
damage such as the cardiovascular (CV) system, kidneys, central nervous system (CNS) …

Determinants of carotid-femoral pulse wave velocity progression in hypertensive patients over a 3.7 years follow-up

P Meani, A Maloberti, P Sormani, G Colombo… - Blood …, 2018 - Taylor & Francis
Objective: The role of risk factors on the progression of arterial stiffness has not yet been
extensively evaluated. The aim of the current longitudinal study was to evaluate the …

Association between high-mobility group box 2 and subclinical hypertension-mediated organ damage in young adults

J Wan, G Liu, S Xia, S Liu, Y Yang… - … in Chronic Disease, 2022 - journals.sagepub.com
Background: Hypertension-mediated organ damage (HMOD) is an emerging problem
among young adults. The potential role of chronic immune-mediated inflammation in the …

Investigation of the Relationship between Cardiovascular Biomarkers and Brachial–Ankle Pulse Wave Velocity in Hemodialysis Patients

PR Chou, PY Wu, PH Wu, TH Huang… - Journal of Personalized …, 2022 - mdpi.com
Brachial–ankle pulse wave velocity (baPWV) and cardiovascular (CV) biomarkers are
correlated with clinical cardiovascular diseases (CVDs) in patients with kidney disease …

Pulse wave velocity progression over a medium‐term follow‐up in hypertensives: Focus on uric acid

A Maloberti, P Rebora, A Andreano… - The Journal of …, 2019 - Wiley Online Library
The role of uric acid (UA) on the arterial stiffness progression has been evaluated only in
three studies. Our aim was to evaluate its role as a possible determinant of the pulse wave …

Annexin A5 knockdown inhibits cardiomyocyte apoptosis and alleviates cardiac hypertrophy via activating the PI3K/AKT/Bcl-2 signaling pathway

L Zhao, H Cao, Y Yuan, C Liao, D Huang, X Li… - Scientific Reports, 2024 - nature.com
Abstract Annexin A5 (ANXA5) is a small calcium-dependent protein that binds specifically to
negatively charged phosphatidylserine as a marker of apoptosis. Previous studies have …

Predicting the risk of portal vein thrombosis in patients with liver cirrhosis and hepatocellular carcinoma

WM Serag, BS eldeen Mohammed, MM Mohamed… - Heliyon, 2020 - cell.com
The mechanisms of the hypercoagulable state in cirrhotics with and without hepatocellular
carcinoma are incompetently comprehended. Objective: We aimed to explore the plasma …

Diagnosis of portal vein thrombosis in cirrhotic patients with and without hepatocellular carcinoma

WM Serag, BE Eysa - Egyptian Liver Journal, 2022 - Springer
Abstract Background The levels of Annexin A5 (Annexin V) were measured in patients with
and without HCC who had liver cirrhosis. These patients were followed for 12 months to …

In healthy normotensive subjects age and blood pressure better predict subclinical vascular and cardiac organ damage than atherosclerosis biomarkers

A Maloberti, F Farina, M Carbonaro, E Piccinelli… - Blood …, 2018 - Taylor & Francis
Purpose: Only few studies evaluated biomarkers useful for defining the cardiovascular risk of
a subject in a pre-clinical condition (ie healthy subjects). In this context we sought to …