Microfabricated integrated DNA analysis system

RA Mathies, R Blazej, C Liu, P Kumaresan… - US Patent …, 2010 - Google Patents
Methods and apparatus for genome analysis are provided. A microfabricated structure
including a microfluidic distribu tion channel is configured to distribute microreactor …

Inline-injection microdevice and microfabricated integrated DNA analysis system using same

RA Mathies, R Blazej, P Kumaresan - US Patent 8,841,116, 2014 - Google Patents
Methods and microfluidic circuitry for inline injection of nucleic acids for capillary
electrophoresis analysis are provided. According to various embodiments, microfabricated …

Microfabricated droplet generator for single molecule/cell genetic analysis in engineered monodispersed emulsions

RA Mathies, P Kumaresan, C Yang… - US Patent 8,454,906, 2013 - Google Patents
Provided are microfluidic designs and methods for rapid gen eration of monodisperse
nanoliter Volume droplets of reagent/target (eg, molecule or cell) mix in emulsion oil. The …

Fluidic devices with diaphragm valves

II Blaga, SB Jovanovich, B Kobrin… - US Patent …, 2013 - Google Patents
The fluidic devices of this invention comprise at least one or a plurality of fluidic conduits in
which fluid flow is con trolled by, for example, on-device diaphragm valves and pumps …

Universal sample preparation system and use in an integrated analysis system

SB Jovanovich, WD Nielsen, DS Cohen… - US Patent …, 2013 - Google Patents
2010-09-16 Assigned to INTEGENX INC. reassignment INTEGENX INC. ASSIGNMENT OF
ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: JOVANOVICH …

Assay apparatus and method using microfluidic arrays

J Linton, K Yoder, R Hess, L Hasan, R Ellis… - US Patent …, 2010 - Google Patents
(57) ABSTRACT A system for holding at least one of sample and reagent for analysis. The
system includes a pair of parallel covers, at least one of Which is light transmissive, of Which …

Microfluidic devices

SB Jovanovich, II Blaga - US Patent 7,745,207, 2010 - Google Patents
Methods and devices for the interfacing of microchips to various types of modules are
disclosed. The technology disclosed can be used as sample preparation and analysis …

Fluid control structures in microfluidic devices

RA Mathies, WH Grover, A Skelley, E Lagally… - US Patent …, 2017 - Google Patents
Methods and apparatus for implementing microfluidic analysis devices are provided. A
monolithic elastomer membrane associated with an integrated pneumatic manifold allows …

Sample preparation, processing and analysis systems

D Eberhart, Y Li, J Ogg, E Van Gelder… - US Patent …, 2020 - Google Patents
2014-10-08 Assigned to INTEGENX INC. reassignment INTEGENX INC. ASSIGNMENT OF
ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: BURGI, DEAN S …

Microfluidic methods

SB Jovanovich, WD Nielsen, M Van Nguyen - US Patent 8,672,532, 2014 - Google Patents
This invention provides microfluidic devices that comprise a fluidics layer having microfluidic
channels and one or more regulating layers that regulate the movement of fluid in the …