Drug markets and pattern of consumption in parts of the world are shifting towards
contamination and opioids like fentanyl as the drug of choice, which dismantles insufficient …

The opioid/overdose crisis in the United States and Canada has claimed hundreds of
thousands of lives and has become a major field for research and interventions. It has …

Overdose deaths involving opioids have increased dramatically since the 1990s, leading to
the worst drug overdose epidemic in US history, but there is limited empirical evidence …

Opioid overdose deaths remain a major public health crisis. We used a system dynamics
simulation model of the US opioid-using population age 12 and older to explore the impacts …

We understand the current crisis of overdose deaths to be driven by widespread opioid use,
characterized by distinct 'waves' of drug use. The first wave was driven by prescription …

Opioid use and the rising case reports of STDs represent co-occurring epidemics; research
indicates that persons who inject drugs (PWID) may be at increased risk for acquiring STDs …

Background After decades of increased opioid pain reliever prescribing, providers are
rapidly reducing prescribing. We hypothesized that reduced access to prescribed opioid …

OBJECTIVES: Misuse of opioid medications (ie, using opioids differently than how a doctor
prescribed the medication) is common among US adolescents and associated with …

The roots of the remarkably lethal US opioid crisis are complex and inextricably entangled
with healthcare, especially in its treatment of another serious health problem: pain. Failures …

In addition to the significance of traumatic experience for high-risk substance use and
addiction, most parts of the system of care ignore the trauma aspect in treatment of …