The high selectivity and affinity of antibodies toward their antigens have made them a highly
valuable tool in disease therapy, diagnosis, and basic research. A plethora of chemical and …

The glycome describes the complete repertoire of glycoconjugates composed of
carbohydrate chains, or glycans, that are covalently linked to lipid or protein molecules …

The majority of monoclonal antibody (mAb) therapeutics possess the ability to engage
innate immune effectors through interactions mediated by their fragment crystallizable (Fc) …

The remarkable progress in engineering and clinical development of therapeutic antibodies
in the last 40 years, after the seminal work by Köhler and Milstein, has led to the approval by …

Capillary electrophoresis has emerged as a powerful approach for carbohydrate analyses
since 2014. The method provides high resolution capable of separating carbohydrates by …

Monoclonal antibodies (mAbs) are one of the most widely used drug platforms for infectious
diseases or cancer therapeutics because they selectively target pathogens, infectious cells …

Therapeutic monoclonal antibodies (mAbs) have become one of the fastest growing classes
of drugs in recent years and are approved for the treatment of a wide range of indications …

Antibodies are immunoglobulins that play essential roles in immune systems. All antibodies
are glycoproteins that carry at least one or more conserved N-linked oligosaccharides (N …

Asthma is a heterogeneous inflammatory disease of the airways that is associated with
airway hyperresponsiveness and airflow limitation. Although asthma was once simply …

Glycosylation can be a critical quality attribute in biologic manufacturing. In particular, it has
implications on the half‐life, immunogenicity, and pharmacokinetics of therapeutic …