H2S-and NO-releasing gasotransmitter platform: A crosstalk signaling pathway in the treatment of acute kidney injury

JC Pieretti, CVC Junho, MS Carneiro-Ramos… - Pharmacological …, 2020 - Elsevier
Acute kidney injury (AKI) is a syndrome affecting most patients hospitalized due to kidney
disease; it accounts for 15% of patients hospitalized in intensive care units worldwide. AKI is …

Emerging medical therapies in crush syndrome–progress report from basic sciences and potential future avenues

N Li, X Wang, P Wang, H Fan, S Hou, Y Gong - Renal Failure, 2020 - Taylor & Francis
Crush injury is a disease that is commonly found in victims of earthquakes, debris flows,
mine disasters, explosions, terrorist attacks, local wars, and other accidents. The …

Heart and kidney H2S production is reduced in hypertensive and older rats

D Szlęzak, T Hutsch, M Ufnal, M Wróbel - Biochimie, 2022 - Elsevier
The prevalence of hypertension increases with age, but the mechanisms linking this
phenomenon are not well understood. Hydrogen sulfide (H 2 S) may be involved in this …

[HTML][HTML] Blue light induces skin apoptosis and degeneration through activation of the endoplasmic reticulum stress-autophagy apoptosis axis: protective role of …

S Zhu, X Li, F Wu, X Cao, K Gou, C Wang… - Journal of Photochemistry …, 2022 - Elsevier
Research on the phototoxicity of blue light (BL) to the skin is increasing. Although blue light
can induce oxidative stress, inflammation, and inhibition of proliferation in skin cells, the …

Paving the way ahead: protocol optimization of mouse models in crush syndrome related acute kidney injury research

O Qiao, X Wang, Z Li, L Han, X Chen… - Frontiers in …, 2024 - frontiersin.org
Backgrounds Crush syndrome (CS) is the leading cause of death after earthquakes, second
only to direct trauma. Acute kidney injury (AKI) is the most severe complication of CS …

[HTML][HTML] Complex Pathophysiology of Acute Kidney Injury (AKI) in Aging: Epigenetic Regulation, Matrix Remodeling, and the Healing Effects of H2S

S Gupta, S Mandal, K Banerjee, H Almarshood… - Biomolecules, 2024 - mdpi.com
The kidney is an essential excretory organ that works as a filter of toxins and metabolic by-
products of the human body and maintains osmotic pressure throughout life. The kidney …

Breaking new ground: standardizing rat models for crush syndrome investigations

D Li, Y Chen, B Yang, W Li, Y Xu, X Wang, Y Teng… - Shock, 2023 - journals.lww.com
Crush syndrome (CS), alternatively termed traumatic rhabdomyolysis, is a paramount
posttraumatic complication. Given the infeasibility of conducting direct simulation research in …

Zinc chelator treatment in crush syndrome model mice attenuates ischemia–reperfusion-induced muscle injury due to suppressing of neutrophil infiltration

Y Haruta, K Kobayakawa, H Saiwai, K Hata… - Scientific reports, 2022 - nature.com
In crush syndrome, massive muscle breakdown resulting from ischemia–reperfusion muscle
injury can be a life-threatening condition that requires urgent treatment. Blood reperfusion …

The functions of hydrogen sulfide on the urogenital system of both males and females: from inception to the present

S Salehiyeh, AF Faiz, M Manzourolhojeh… - Naunyn-Schmiedeberg's …, 2024 - Springer
Hydrogen sulfide (H2S) is known as a chemical gas in nature with both enzymatic and non-
enzymatic biosynthesis in different human organs. A couple of studies have demonstrated …

[HTML][HTML] Mini review of biochemical basis, diagnosis and management of crush syndrome

A Hamlah, H Al-Madhagi - Acta medica Lituanica, 2023 - ncbi.nlm.nih.gov
Crush syndrome (CS) is a metabolic disorder whose victims are individuals suffered from
natural disasters such as earthquake or man-made conflicts. CS complications include acute …