A critical review on the particle generation and other applications of rapid expansion of supercritical solution
The novel particle generation processes of Active Pharmaceutical Ingredient (API)/drug
have been extensively explored in recent decades due to their wide-range applications in …
have been extensively explored in recent decades due to their wide-range applications in …
Using the supercritical carbon dioxide as the solvent of Nystatin: Studying the effect of co-solvent, experimental and correlating
The solubility of Nystatin in supercritical CO 2 at 308–338 K and 12–30 MPa, with or without
a co-solvent, was determined. Additionally, the effect of utilizing ethanol as a co-solvent was …
a co-solvent, was determined. Additionally, the effect of utilizing ethanol as a co-solvent was …
Solubility of Lacosamide in supercritical carbon Dioxide: An experimental analysis and thermodynamic modeling
N Esfandiari, SA Sajadian - Journal of Molecular Liquids, 2022 - Elsevier
Lacosamide has been used to control partial-onset seizures (seizures that involve only one
part of the brain) in adults and children. In this article, Lacosamide solubility in the SC-CO 2 …
part of the brain) in adults and children. In this article, Lacosamide solubility in the SC-CO 2 …
Solubility of montelukast (as a potential treatment of COVID-19) in supercritical carbon dioxide: Experimental data and modelling
The solubility behavior of the pharmaceutical materials in a supercritical fluid is very
important to produce the micro/nano-sized drug particulates. In the current study, solubility of …
important to produce the micro/nano-sized drug particulates. In the current study, solubility of …
Solubility of Ketoconazole (antifungal drug) in SC-CO2 for binary and ternary systems: measurements and empirical correlations
G Sodeifian, SA Sajadian, F Razmimanesh… - Scientific Reports, 2021 - nature.com
One of the main steps in choosing the drug nanoparticle production processes by
supercritical carbon dioxide (SC-CO2) is determining the solubility of the solid solute. For …
supercritical carbon dioxide (SC-CO2) is determining the solubility of the solid solute. For …
Experimental measurement and thermodynamic modeling of capecitabine (an anticancer drug) solubility in supercritical carbon dioxide in a ternary system: effect of …
NS Ardestani, NY Majd, M Amani - Journal of Chemical & …, 2020 - ACS Publications
Solubility of capecitabine (CPT) in a ternary system (supercritical carbon dioxide (sc-CO2)+
CPT+[methanol, ethanol, and dimethyl sulfoxide (DMSO)] as cosolvents) was measured at …
CPT+[methanol, ethanol, and dimethyl sulfoxide (DMSO)] as cosolvents) was measured at …
Measurement and thermodynamic modeling of solubility of Tamsulosin drug (anti cancer and anti-prostatic tumor activity) in supercritical carbon dioxide
SM Hazaveie, G Sodeifian, SA Sajadian - The Journal of Supercritical …, 2020 - Elsevier
Among available methods, supercritical fluid (SCF) technology is a new and suitable
approach for producing nano-sized particles. For this purpose, determination of a solid …
approach for producing nano-sized particles. For this purpose, determination of a solid …
Investigating the thermal enhancement of Levetiracetam solubility in the ternary system of supercritical carbon dioxide and ethanol
The successful implementation of supercritical carbon dioxide technology in the production
of new drugs with enhanced bioavailability necessitates an assessment of the solubility of …
of new drugs with enhanced bioavailability necessitates an assessment of the solubility of …
Experimental measurement of solubilities of sertraline hydrochloride in supercriticalcarbon dioxide with/without menthol: Data correlation
G Sodeifian, SA Sajadian - The Journal of Supercritical Fluids, 2019 - Elsevier
For the first time, the solubilities of sertraline hydrochloride in SC-CO 2, as a binary system,
and SC-CO 2+ menthol, as a ternary system, were determined. Experimental data was …
and SC-CO 2+ menthol, as a ternary system, were determined. Experimental data was …
[HTML][HTML] Thermodynamic and experimental analysis of drug nanoparticles preparation using supercritical thermal processing: Solubility of Chlorothiazide in different …
AJ Obaidullah - Case Studies in Thermal Engineering, 2023 - Elsevier
Background/purpose Chlorothiazide is a well-known diuretic and an antihypertensive drug
with poor solubility and permeability and thus low bioavailability. Producing nanoparticles of …
with poor solubility and permeability and thus low bioavailability. Producing nanoparticles of …