Important shapeshifter: mechanisms allowing astrocytes to respond to the changing nervous system during development, injury and disease

J Schiweck, BJ Eickholt, K Murk - Frontiers in cellular neuroscience, 2018 - frontiersin.org
Astrocytes are the most prevalent glial cells in the brain. Historically considered as “merely
supporting” neurons, recent research has shown that astrocytes actively participate in a …

Circadian control of BDNF-mediated Nrf2 activation in astrocytes protects dopaminergic neurons from ferroptosis

T Ishii, E Warabi, GE Mann - Free Radical Biology and Medicine, 2019 - Elsevier
Astrocyte-neuron interactions protect neurons from iron-mediated toxicity. As dopamine can
be metabolized to reactive quinones, dopaminergic neurons are susceptible to oxidative …

Helicobacter pylori outer membrane vesicles induce astrocyte reactivity through nuclear factor-κappa B activation and cause neuronal damage in vivo in a murine …

E Palacios, L Lobos-González, S Guerrero… - Journal of …, 2023 - Springer
Abstract Background Helicobacter pylori (Hp) infects the stomach of 50% of the world's
population. Importantly, chronic infection by this bacterium correlates with the appearance of …

[HTML][HTML] Cell adhesion and matricellular support by astrocytes of the tripartite synapse

AEJ Hillen, JPH Burbach, EM Hol - Progress in neurobiology, 2018 - Elsevier
Astrocytes contribute to the formation, function, and plasticity of synapses. Their processes
enwrap the neuronal components of the tripartite synapse, and due to this close interaction …

Grading the commercial optical biosensor literature—Class of 2008:'The Mighty Binders'

RL Rich, DG Myszka - Journal of Molecular Recognition: An …, 2010 - Wiley Online Library
Optical biosensor technology continues to be the method of choice for label‐free, real‐time
interaction analysis. But when it comes to improving the quality of the biosensor literature …

Thy-1 (CD90) promotes bone formation and protects against obesity

AK Picke, GM Campbell, M Blüher, U Krügel… - Science translational …, 2018 - science.org
Osteoporosis and obesity result from disturbed osteogenic and adipogenic differentiation
and present emerging challenges for our aging society. Because of the regulatory role of …

Thy‐1: more than a marker for mesenchymal stromal cells

A Saalbach, U Anderegg - The FASEB Journal, 2019 - Wiley Online Library
Balanced differentiation of mesenchymal stromal cells (MSCs) into osteoblasts and
adipocytes is essential for healthy bone and fat homeostasis. A disturbed balance of MSC …

Role of astrocytes in synapse formation and maturation

CX Tan, CJB Lane, C Eroglu - Current topics in developmental biology, 2021 - Elsevier
Astrocytes are the most abundant glial cells in the mammalian brain and directly participate
in the proper functioning of the nervous system by regulating ion homeostasis, controlling …

[HTML][HTML] STAT3-mediated signaling dysregulates lung fibroblast-myofibroblast activation and differentiation in UIP/IPF

DV Pechkovsky, CM Prêle, J Wong… - The American journal of …, 2012 - Elsevier
STAT3 is a latent transcription factor that plays a role in regulating fibroblast function in
fibrotic lung diseases. To further understand the role of STAT3 in the phenotypic divergence …

Thy-1 dependent uptake of mesenchymal stem cell-derived extracellular vesicles blocks myofibroblastic differentiation

TP Shentu, TS Huang, M Cernelc-Kohan, J Chan… - Scientific reports, 2017 - nature.com
Bone marrow-derived mesenchymal stem cells (MSC) have been promoted for multiple
therapeutic applications. Many beneficial effects of MSCs are paracrine, dependent on …