Trypanosoma brucei provides an excellent system for studies of many aspects of cell
biology, including cell structure and morphology, organelle positioning, cell division and …

Kinetoplast DNA (kDNA) is the most structurally complex mitochondrial DNA in nature.
Unique to the single mitochondrion of unicellular ffagellates of the order Kinetoplastida …

Kinetoplastid protozoa such as trypanosomes and Leishmania are important because they
cause human disease. These parasites are named after one of their most unusual features …

Approaches which eliminate mRNA expression directly are ideally suited for reverse
genetics applications in eukaryotic microbes which are asexual diploids, such as the …

RNA interference or RNAi is defined as the mechanism through which gene‐specific, double‐
stranded RNA (dsRNA) triggers degradation of homologous transcripts. Besides providing …

Flagella and cilia are elaborate cytoskeletal structures conserved from protists to mammals,
where they fulfil functions related to motility or sensitivity. Here we demonstrate novel roles …

Kinetoplastids are flagellated protozoans, whose members include the pathogens
Trypanosoma brucei, T. cruzi and Leishmania species, that are considered among the …

Salivarian trypanosomes are the causative agents of several diseases of major social and
economic impact. The most infamous parasites of this group are the African subspecies of …

Parasitic protozoa comprise diverse aetiological agents responsible for important diseases
in humans and animals including sleeping sickness, Chagas disease, leishmaniasis …

The composition of the large, single, mitochondrion (mt) of Trypanosoma brucei was
characterized by MS (2‐D LC‐MS/MS and gel‐LC‐MS/MS) analyses. A total of 2897 …