[HTML][HTML] Divergent landscapes of A-to-I editing in postmortem and living human brain

M Rodriguez de los Santos, BH Kopell… - nature …, 2024 - nature.com
Abstract Adenosine-to-inosine (A-to-I) editing is a prevalent post-transcriptional RNA
modification within the brain. Yet, most research has relied on postmortem samples …

[HTML][HTML] Divergent landscapes of A-to-I editing in postmortem and living human brain

MR de Los Santos, BH Kopell, AB Grice, G Ganesh… - medRxiv, 2024 - ncbi.nlm.nih.gov
Abstract Adenosine-to-inosine (A-to-I) editing is a prevalent post-transcriptional RNA
modification within the brain. Yet, most research has relied on postmortem samples …

Multiomic foundations of human prefrontal cortex tissue function

BH Kopell, DA Kaji, LE Liharska, E Vornholt… - medRxiv, 2024 - medrxiv.org
The prefrontal cortex (PFC) is a region of the brain that in humans is involved in the
production of higher-order functions such as cognition, emotion, perception, and behavior …

Characterising processing conditions that artifactually bias human brain tissue transcriptomes

JA Stratton, M Yaqubi, M Thomas, J Talbot-Martin… - 2024 - researchsquare.com
Autopsy-derived brain tissue analysis is vital for exploring the complex landscape of
neurobiology in health and disease but processing conditions during post-mortem handling …