Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19

Y Peng, AJ Mentzer, G Liu, X Yao, Z Yin, D Dong… - Nature …, 2020 - nature.com
The development of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
vaccines and therapeutics will depend on understanding viral immunity. We studied T cell …

HIV-2 as a model to identify a functional HIV cure

J Esbjörnsson, M Jansson, S Jespersen… - AIDS research and …, 2019 - Springer
Two HIV virus types exist: HIV-1 is pandemic and aggressive, whereas HIV-2 is confined
mainly to West Africa and less pathogenic. Despite the fact that it has been almost 40 years …

Long-term follow-up of HIV-2-related AIDS and mortality in Guinea-Bissau: a prospective open cohort study

J Esbjörnsson, F Månsson, A Kvist, ZJ da Silva… - The lancet HIV, 2019 - thelancet.com
Summary Background HIV type 2 (HIV-2) is considered more benign and has fewer
pathogenic consequences than HIV type 1 (HIV-1) for most infected individuals. However …

Engineering broadly neutralizing antibodies for HIV prevention and therapy

CK Hua, ME Ackerman - Advanced drug delivery reviews, 2016 - Elsevier
A combination of advances spanning from isolation to delivery of potent HIV-specific
antibodies has begun to revolutionize understandings of antibody-mediated antiviral activity …

The long-term effects of a family based economic empowerment intervention (Suubi+ Adherence) on suppression of HIV viral loads among adolescents living with HIV …

FM Ssewamala, D Dvalishvili, CA Mellins, EH Geng… - PLoS …, 2020 - journals.plos.org
Background The rapid scale-up of HIV therapy across Africa has failed to adequately
engage adolescents living with HIV (ALWHIV). Retention and viral suppression for this …

Polyfunctional T-cell signatures to predict protection from cytomegalovirus after lung transplantation

LD Snyder, C Chan, D Kwon, JS Yi… - American Journal of …, 2016 - atsjournals.org
Rationale: Cytomegalovirus (CMV), which is one of the most common infections after lung
transplantation, is associated with chronic lung allograft dysfunction and worse post …

Primary role of type I interferons for the induction of functionally optimal antigen-specific CD8+ T cells in HIV infection

MP Cabral-Piccin, L Papagno, X Lahaye… - …, 2023 - thelancet.com
Background CD8+ T cells equipped with a full arsenal of antiviral effector functions are
critical for effective immune control of HIV-1. It has nonetheless remained unclear how best …

Effect of a Russian-backbone live-attenuated influenza vaccine with an updated pandemic H1N1 strain on shedding and immunogenicity among children in The …

BB Lindsey, YJ Jagne, EP Armitage… - The Lancet …, 2019 - thelancet.com
Background The efficacy and effectiveness of the pandemic H1N1 (pH1N1) component in
live attenuated influenza vaccine (LAIV) is poor. The reasons for this paucity are unclear but …

The long-term (5-year) impact of a family economic empowerment intervention on adolescents living with HIV in Uganda: Analysis of longitudinal data from a cluster …

R Brathwaite, FM Ssewamala, M Mutumba… - AIDS and Behavior, 2022 - Springer
Abstract 150/150 words. We examined the 5-year impact of an economic empowerment (EE)
intervention on: adherence, viral suppression, sexual risk-taking intentions (primary); and …

A high prevalence of potential HIV elite controllers identified over 30 years in Democratic Republic of Congo

MG Berg, A Olivo, BJ Harris, MA Rodgers, L James… - …, 2021 - thelancet.com
Background In-depth analysis of the HIV pandemic at its epicenter in the Congo basin has
been hampered by 40 years of political unrest and lack of functional public health …