Human Th17 pro-inflammatory cells are currently defined as cells that produce IL-17A and F,
tumor necrosis factor (TNF)-α, IL-6, IL-21, IL-22 and IL-23. Recently discovered related …

Morphea, also known as localized scleroderma, encompasses a group of idiopathic sclerotic
skin diseases. The spectrum ranges from relatively mild phenotypes, which generally cause …

Localized scleroderma (LS) is a complex disease characterized by a mixture of inflammation
and fibrosis of the skin that, especially in the pediatric population, also affects …

Morphea is a rare autoimmune condition causing inflammation and sclerosis of the skin and
underlying soft tissue. It is characterized by periods of activity (inflammation admixed with …

Objective To evaluate peripheral blood T-helper (TH) cell-associated cytokine and
chemokine profiles in localized scleroderma (LS), and correlate them with clinical disease …

Background Localized scleroderma (LS) is a rare chronic immune-mediated skin condition
of unknown etiology characterized by an inflammatory response in the skin and …

Lichen planus is considered a chronic inflammatory disease which affects different sites,
such as the skin, mucous membranes, hair, and nails. Based on the evidence, a complex …

The incidence of immune-mediated inflammatory diseases (IMIDs) is on the rise. A high salt
content in the diet was found to play a crucial role in mediating IMIDs. It was demonstrated …

Objectives This case series explores the potential efficacy of Abatacept in patients
presenting with morphea subtypes and deep tissue involvement. Methods Three patients …

Introduction Morphea is a chronic autoimmune fibrosing condition of the skin and underlying
tissue with the potential for significant disease-associated morbidity. While the exact etiology …