To date, molecular genetic analyses have identified over 500 distinct DNA variants in five
disease genes associated with familial Parkinson disease; α‐synuclein (SNCA), parkin …

Introduction Variants in the leucine-rich repeat kinase 2 gene (LRRK2) are risk factors for
Parkinson's disease (PD), but their prevalence varies geographically, reflecting the locations …

Parkinson's disease (PD) and atypical parkinsonian syndromes (APS) are symptomatically
characterized by parkinsonism, with the latter presenting additionally a distinctive range of …

Parkinson's Disease (PD) is a chronic neurodegenerative disorder characterized by motor
and non-motor symptoms, among which are bradykinesia, rigidity, tremor as well as mental …

Introducción Conocer el alcance socieoeconómico de la enfermedad de Parkinson es
esencial para la planificación de recursos y concienciación social. Desarrollo Se ha …

Abstract Background The Iberian Peninsula stands out as having variable levels of
population admixture and isolation, making Spain an interesting setting for studying the …

Brain cholesterol metabolism has been described as altered in Parkinson's disease (PD)
patients. Serum lipid levels have been widely studied in PD with controversial results among …

Objectives VPS35 and VPS13 have been associated with Parkinson's disease (PD), and
their shared phenotype in yeast when reduced in function is abnormal vacuolar transport …

Leucine-rich repeat kinase 2 (LRRK2) is a large protein kinase that physiologically
phosphorylates and regulates the function of several Rab proteins. LRRK2 is genetically …

Introduction Understanding the social and economic impact of Parkinson's disease is
essential for resource planning and raising social awareness. Development Researchers …