Microgravity and space radiation are hazards of spaceflight that have deleterious effects on
articular cartilage. Since it is not widely monitored or protected through dedicated …

This review summarizes the current literature available on joint cartilage alterations in long-
duration spaceflight. Evidence from spaceflight participants is currently limited to serum …

To evaluate the individual responses in skeletal muscle outcomes following bed rest, data
from three studies (21-day PlanHab; 10-day FemHab and LunHab) were combined …

New Findings What is the central question of this study? Do females and males exhibit a
similar sarcopenic response as a consequence of normoxic and hypoxic bed rest? What is …

Purpose Hypobaric hypoxic habitats are currently being touted as a potential solution to
minimise decompression procedures in preparation for extra vehicular activities during …

As a common clinical disease, fracture is often accompanied by pain, swelling, bleeding as
well as other symptoms and has a high disability rate, even threatening life, seriously …

Individual variation is of interest to Space Agency's, which cannot be explored with
astronauts due to anonymity. We retrospectively analysed data collected throughout three …

Mechanical load is important for the development, maintenance, and regeneration of healthy
musculoskeletal tissues, including articular cartilage. Elucidating the association between …

Hematological changes are commonly observed following prolonged exposure to hypoxia
and bed rest. Typically, such responses have been reported as means and standard …

Hemiarthroplasties typically result in accelerated wear of the preserved side of the joint,
resulting in suboptimal clinical outcomes and limited longevity. This in vitro study …