EM Hol, M Pekny - Current opinion in cell biology, 2015 - Elsevier
Glial fibrillary acidic protein (GFAP) is the hallmark intermediate filament (IF; also known as nanofilament) protein in astrocytes, a main type of glial cells in the central nervous system …
Glial fibrillary acidic protein (GFAP), an astrocytic cytoskeletal protein, can be measured in blood samples, and has been associated with Alzheimer's disease (AD). However, plasma …
M Pekny, M Pekna - Physiological reviews, 2014 - journals.physiology.org
Astrocytes are the most abundant cells in the central nervous system (CNS) that provide nutrients, recycle neurotransmitters, as well as fulfill a wide range of other homeostasis …
V Karri, M Schuhmacher, V Kumar - Environmental toxicology and …, 2016 - Elsevier
Human exposure to toxic heavy metals is a global challenge. Concurrent exposure of heavy metals, such as lead (Pb), cadmium (Cd), arsenic (As) and methylmercury (MeHg) are …
S Pöyhönen, S Er, A Domanskyi… - Frontiers in physiology, 2019 - frontiersin.org
Astrocytes, oligodendrocytes, and microglia are abundant cell types found in the central nervous system and have been shown to play crucial roles in regulating both normal and …
Glial fibrillary acidic protein (GFAP) is the main intermediate filament protein in mature astrocytes, but also an important component of the cytoskeleton in astrocytes during …
M Pekny, M Pekna - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2016 - Elsevier
Astrocytes maintain the homeostasis of the central nervous system (CNS) by eg recycling of neurotransmitters and providing nutrients to neurons. Astrocytes function also as key …
It is now well established that the glial fibrillary acidic protein (GFAP) is the principal 8–9 nm intermediate filament in mature astrocytes of the central nervous system (CNS). Over a …
M Pekny, M Nilsson - Glia, 2005 - Wiley Online Library
Astrocytes become activated (reactive) in response to many CNS pathologies, such as stroke, trauma, growth of a tumor, or neurodegenerative disease. The process of astrocyte …