Structural and functional anatomy of the globular domain of complement protein C1q

U Kishore, R Ghai, TJ Greenhough, AK Shrive… - Immunology letters, 2004 - Elsevier
C1q is the first subcomponent of the classical pathway of the complement system and a
major connecting link between innate and acquired immunity. As a versatile charge pattern …

Retrovirus envelope glycoproteins

E Hunter, R Swanstrom - Retroviruses: Strategies of Replication, 1990 - Springer
The envelope glycoprotein complex of replication competent retroviruses is comprised of
two polypeptides, an external, glycosylated, hydrophilic polypeptide (SU) and a membrane …

Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS

RC Gallo, SZ Salahuddin, M Popovic, GM Shearer… - science, 1984 - science.org
Peripheral blood lymphocytes from patients with the acquired immunodeficiency syndrome
(AIDS) or with signs or symptoms that frequently precede AIDS (pre-AIDS) were grown in …

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

AG Dalgleish, PCL Beverley, PR Clapham… - Nature, 1984 - nature.com
Acquired immune deficiency syndrome (AIDS) is characterized by opportunistic infections
and by 'opportunistic neoplasms'(for example, Kaposi's sarcoma) 1. Persistent generalized …

Detection, isolation, and continuous production of cytopathic retroviruses (HTLV-III) from patients with AIDS and pre-AIDS

M Popovic, MG Sarngadharan, E Read, RC Gallo - Science, 1984 - science.org
A cell system was developed for the reproducible detection of human T-lymphotropic
retroviruses (HTLV family) from patients with the acquired immunodeficiency syndrome …

[HTML][HTML] The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain

PJ Maddon, AG Dalgleish, JS McDougal, PR Clapham… - Cell, 1986 - cell.com
The isolation of clones encoding the human surface protein T4, and the expression of the T4
gene in new cellular environments, have enabled us to examine the role of this protein in the …

Complete nucleotide sequence of the AIDS virus, HTLV-III

L Ratner, W Haseltine, R Patarca, KJ Livak, B Starcich… - Nature, 1985 - nature.com
The complete nucleotide sequence of two human T-cell leukaemia type III (HTLV-III) proviral
DNAs each have four long open reading frames, the first two corresponding to the gag and …

Spread of HTLV-I between lymphocytes by virus-induced polarization of the cytoskeleton

T Igakura, JC Stinchcombe, PKC Goon, GP Taylor… - Science, 2003 - science.org
Cell contact is required for efficient transmission of human T cell leukemia virus–type 1
(HTLV-I) between cells and between individuals, because naturally infected lymphocytes …

Grain boundary scars and spherical crystallography

AR Bausch, MJ Bowick, A Cacciuto, AD Dinsmore… - Science, 2003 - science.org
We describe experimental investigations of the structure of two-dimensional spherical
crystals. The crystals, formed by beads self-assembled on water droplets in oil, serve as …

Induction of CD4-dependent cell fusion by the HTLV-III/LAV envelope glycoprotein

JD Lifson, MB Feinberg, GR Reyes, L Rabin… - Nature, 1986 - nature.com
Formation of syncytia, with progression to cell death, is a characteristic feature of in vitro
cultures of susceptible cells infected with human T-lymphotropic virus type …