Expanding the structural diversity of polyelectrolyte complexes and polyzwitterions

AE Neitzel, GX De Hoe, MV Tirrell - Current Opinion in Solid State and …, 2021 - Elsevier
Charged (macro) molecules are essential components in natural materials and organisms;
thus the rational design of biomimetic materials requires a holistic understanding of structure …

Biodegradable zwitterionic polymers as PEG alternatives for drug delivery

Z Zhang, H Sun, J Giannino, Y Wu… - Journal of Polymer …, 2024 - Wiley Online Library
Abstract Poly (ethylene glycol)(PEG) is a highly biocompatible and water‐soluble polymer
that is widely utilized for biomedical applications. Unfortunately, the immunogenicity and …

Radio-sensitivity enhancement in HT29 cells through magnetic hyperthermia in combination with targeted nano-carrier of 5-Flourouracil

PS Mirzaghavami, S Khoei, S Khoee… - Materials Science and …, 2021 - Elsevier
Normal tissue complication and development of radioresistance in cancer cells are known
as the main challenges of ionizing radiation treatment. In the current study, we intended to …

Well-defined pH-responsive self-assembled block copolymers for the effective codelivery of doxorubicin and antisense oligonucleotide to breast cancer cells

MA Mohamed, L Yan, A Shahini… - ACS Applied Bio …, 2022 - ACS Publications
The worldwide steady increase in the number of cancer patients motivates the development
of innovative drug delivery systems for combination therapy as an effective clinical modality …

Well-defined pH-sensitive self-assembled triblock copolymer-based crosslinked micelles for efficient cancer chemotherapy

MA Mohamed, A Singh, PN Prasad, C Cheng - Molecules, 2022 - mdpi.com
Delivery of chemotherapeutics to cancer cells using polymeric micelles is a promising
strategy for cancer treatment. However, limited stability of micelles, premature drug release …

Effect of the side chain composition of mixed-charge polymers on pH-selective cell–membrane interactions

Y Nakamura, M Nasu, Y Shindo, K Oka, D Citterio… - Polymer Journal, 2023 - nature.com
Zwitterionic polymers are characterized by their antifouling ability due to their net-neutral
charge and affinity for cancer cell surfaces. We developed six pH-responsive mixed-charge …

Well-Defined Diblock Poly(ethylene glycol)-b-Poly(ε-caprolactone)-Based Polymer-Drug Conjugate Micelles for pH-Responsive Delivery of Doxorubicin

A Jafari, L Yan, MA Mohamed, Y Wu, C Cheng - Materials, 2020 - mdpi.com
Nanoparticles have emerged as versatile carriers for various therapeutics and can
potentially treat a wide range of diseases in an accurate and disease-specific manner …

High Molecular Weight Poly (ethylenimine)‐Based Water‐Soluble Lipopolymer for Transfection of Cancer Cells

HAH Abd Elhameed, D Ungor, N Igaz… - Macromolecular …, 2020 - Wiley Online Library
Over the past decade, search for novel materials for nucleic acid delivery has prompted a
special interest in polymeric nanoparticles (NPs). In this study, the biological applicability of …

[PDF][PDF] LIPID POLYMER-BASED BIO-INSPIRED DRUG DELIVERY SYSTEM

R Ahuja, MM Rane - academia.edu
Gene targeting has been a promising drug delivery system, thereby helping to improve the
impaired functioning in various disorders." Lipoplexes" and" Polyplexes" incorporates lipids …

PEGylated Block Copolymer for Cancer Imaging and Treatment

S Singh - 2020 - search.proquest.com
Gene theranostics have emerged as an important tool for the treatment of cancer as well as
other diseases. Among the challenges in this field is the lack of effective vectors to …