DNA methylation is an epigenetic mark that regulates multiple processes, such as gene
expression and genome stability. Mutants and pharmacological treatments have been …

Adenosine triphosphate‐dependent chromatin remodeling complexes are important for the
regulation of transcription, DNA replication, and genome stability in eukaryotes. Although …

DNA methylation is a major epigenetic modification found across species and has a
profound impact on many biological processes. However, its influence on chromatin …

Elucidation of both the three-dimensional structure and the dynamics of a protein is essential
to understand its function. Technical breakthroughs in single-particle analysis based on cryo …

Over millions of years, eukaryotes evolved from unicellular to multicellular organisms with
increasingly complex genomes and sophisticated gene expression networks. Consequently …

The Microrchidia (MORC) family of ATPases are required for transposable element (TE)
silencing and heterochromatin condensation in plants and animals, and C. elegans MORC …

Flowering plants utilize small RNA (sRNA) molecules to guide DNA methyltransferases to
genomic sequences. This RNA-directed DNA methylation (RdDM) pathway preferentially …

Abstract MORPHEUS'MOLECULE1 (MOM1) is an Arabidopsis factor previously shown to
mediate transcriptional silencing independent of major DNA methylation changes. Here we …

Key message BPM1 interacts with components of the DDR complex and stimulates DNA
methylation at CHH sites, suggesting its involvement in the RdDM methylation pathway. The …

The RNA-directed DNA methylation (RdDM) pathway plays an essential role in the
transposon silencing mechanism; the DDR complex, consisting of DRD1, DMS3, and RDM1 …