The global prevalence of nonalcoholic fatty liver disease (NAFLD) has dramatically
increased in parallel with the epidemic of obesity. Controversy has emerged around dietary …

Epidemiological studies have shown a positive relationship between dietary fat intake and
obesity. Since rats and mice show a similar relationship, they are considered an appropriate …

Over 50 years of research has sought to define the role dietary fat plays in cardiovascular
disease (CVD) risk. Although optimal dietary fat quantity has been keenly pursued over past …

Palmitic acid (PA) is the most common fatty acid in humans and mediates palmitoylation
through its conversion into palmitoyl coenzyme A. Although palmitoylation affects many …

This review highlights the inflammatory and insulin-antagonizing effects of saturated fatty
acids (SFA), which contribute to the development of metabolic syndrome. Mechanisms …

This Opinion of the EFSA Panel on Dietetic Products, Nutrition, and Allergies (NDA) deals
with the setting of Dietary Reference Values (DRVs) for fats. A lower bound of the reference …

Emerging evidence shows that palmitic acid (PA), a common fatty acid in the human diet,
serves as a signaling molecule regulating the progression and development of many …

The prevalence of obesity has grown to an alarming level of at least 300 million people
worldwide. Additionally, a diabetes epidemic is underway, with an estimate of 217 million …

Obesity is associated with an increased risk of several major noncommunicable diseases,
and is an important public health concern globally. Dietary fat content is a major contributor …

Human metabolic diseases can be mimicked in rodents by using dietary interventions such
as high fat diets (HFD). Nonalcoholic fatty liver disease (NAFLD) develops as a result of HFD …