The extracellular matrix (ECM) is a complex, dynamic network present within all tissues and
organs that not only acts as a mechanical support and anchorage point but can also direct …

The integration of tumor-on-a-chip technology with mini-tissues or organoids has emerged
as a powerful approach in cancer research and drug development. This review provides an …

The field of organ-on-a-chip engineering is focused on dynamically controlling the
microphysiological environments that the cells are surrounded by in order to produce …

The number of successful drug development projects has been stagnant for decades
despite major breakthroughs in chemistry, molecular biology, and genetics. Unreliable target …

Cardiovascular diseases are caused by hereditary factors, environmental conditions, and
medication-related issues. On the other hand, the cardiotoxicity of drugs should be …

Drug discovery and toxicology is a complex process that involves considerable basic
research and preclinical evaluation. These depend highly on animal testing which often fails …

Pancreatic in vitro research is of major importance to advance mechanistic understanding
and development of treatment options for diseases such as diabetes mellitus. We present a …

Abstract Lung‐on‐chips (LoCs) are advanced microsystems designed to culture pulmonary
cells under physiologically relevant conditions, including air–liquid interface, cell stretch …

In the realm of precise medicine, the advancement of manufacturing technologies is vital for
enhancing the capabilities of medical devices such as nano/microrobots …

Epithelium and endothelium, occupying a significant proportion of cells in the human body,
play a crucial role in maintaining organs' normal structure and function. Various methods …