Major depression is a debilitating and recurrent disorder with a substantial lifetime risk and a
high social cost. Depressed patients generally display co-morbid symptoms, and depression …

GOTTESMANN, C. The transition from slow-wave sleep to paradoxical sleep: Evolving facts
and concepts of the neurophysiological processes underlying the intermediate stage of …

Ever since the discovery of rapid eye movement sleep (REMS), studies have been
undertaken to understand its necessity, function and mechanism of action on normal …

Normal cellular metabolism produces oxidants that are neutralized by the cells' antioxidant
enzymes and antioxidants taken from outside. An imbalance between oxidant and …

Rapid eye movement (REM) sleep loss impairs several physiological, behavioral and
cellular processes; however, the mechanism of action was unknown. To understand the …

Sojourners to high altitude experience poor-quality of sleep due to hypobaric hypoxia (HH).
Brain neurotransmitters are the key regulators of sleep wakefulness. Scientific literature has …

Sleep and wakefulness are instinctive behaviours that are present across the animal
species. Rapid eye movement (REM) sleep is a unique biological phenomenon expressed …

The norepinephrinergic neurons in the locus coeruleus (LC) cease firing during REM sleep
(REMS) and increase firing during REMS deprivation. Most of the earlier studies used lesion …

Analyzing ground-breaking research, this reference highlights the impact of sleep
deprivation on the well-being of the individual and society-presenting current theories on the …

Sleep deprivation exerts antidepressant effects after only one night of deprivation,
demonstrating that a rapid antidepressant response is possible. In this report we tested the …