IVD test is a crucial component of clinical care that performs a diagnostic test on biological
samples that have been taken from a living body, such as blood, urine, and tissue.(1) Such …

Nucleic acid is the main material for storing, copying, and transmitting genetic information.
Gene sequencing is of great significance in DNA damage research, gene therapy, mutation …

The recently reported freezing-based labeling method for constructing DNA-AuNP probes is
rapid but still requires thiol modification. Here, we evaluated a poly (A)-tagged DNA …

Gold-nanoparticles-based colorimetric assay is an attractive detection format, but is limited
by the tedious and ineffective posthybridization manipulations for genomic analysis. Here …

Colorimetric detection of target analytes with high specificity and sensitivity is of fundamental
importance to clinical and personalized point-of-care diagnostics. Because of their …

In vitro biosensors have been an integral component for early diagnosis of cancer in the
clinic. Among them, no-wash biosensors, which only depend on the simple mixing of the …

Biosensors can convert the concentration of biological analytes into an electrical signal or
other signals for detection. They are widely used in medical diagnostics, food safety, process …

Nucleic acids are important biomarkers related to diseases of cancer, infectious, and genetic
disorders. As a kind of indicator, gold nanoparticles (AuNPs) can generate colored signals …

Graphene is scientifically and commercially important because of its unique molecular
structure which is monoatomic in thickness, rigorously two-dimensional and highly …

Gold based structures such as nanoparticles (NPs) and nanowires (NWs) have widely been
used as building blocks for sensing devices in chemistry and biochemistry fields because of …