VM Cardoso, SAH Paredes, G Campani… - Applied Microbiology …, 2022 - Springer
Several studies have searched for new antigens to produce pneumococcal vaccines that are more effective and could provide broader coverage, given the great number of serotypes …
An unstructured–unsegregated temperature-dependent kinetic model was developed and validated to describe ethanol fermentation in a mixture of xylose and glucose for the …
The integration of state estimation and control is a promising approach to overcome challenges related to unavailable or noisy online measurements and plant-model mismatch …
S Vazulka, M Schiavinato, M Wagenknecht… - ACS Synthetic …, 2022 - ACS Publications
Antibody fragments such as Fab's require the formation of disulfide bonds to achieve a proper folding state. During their recombinant, periplasmic expression in Escherichia coli …
HHM da Costa, M Bielavsky, DJB Orts, S Araujo… - International journal of …, 2023 - mdpi.com
The Zika Virus (ZIKV) is an emerging arbovirus of great public health concern, particularly in the Americas after its last outbreak in 2015. There are still major challenges regarding …
E Mercado, S Mbiki, SW Harcum… - Biochemical Engineering …, 2023 - Elsevier
In the biopharmaceutical industry, accurate prediction of the oxygen uptake rate (OUR) is critical to understanding cell health, where OUR is related to the oxygen transfer rate (OTR) …
JC Mestre, MO Cerri, MN Esperança… - Journal of Chemical …, 2019 - Wiley Online Library
Background Determination of the volumetric oxygen transfer coefficient (kLa) plays an important role in the design and characterization of bioreactors. Among all methods …
E Yatmaz, I Turhan - Essentials in fermentation technology, 2019 - Springer
Liquid culture and solid culture fermentation are widely used to produce a range of metabolites. Despite the use of solid culture fermentation in some cases, most fermentations …
Escherichia coli (E. coli) is the most common host for recombinant protein production. A high cell density culture (HCDC) of E. coli is regarding be an efficient way to improve recombinant …