Continuous oxidation of carbohydrates, lipids, and amino acids generate extremely reactive
carbonyl species (RCS). Human body comprises some important RCS namely hexanal …

Acute traumatic spinal cord injury (SCI) is marked by the enhanced production of local
cytokines and pro-inflammatory substances that induce gliosis and prevent reinnervation …

Peripheral neuropathy and cognitive impairments following cisplatin administration may
interfere with the clinical usage of the drug. Mesna is a chemoprotective agent with anti …

Aims The current study aimed to elucidate the neurotoxic potential of DOX to induce AD-like
pathology paying attention to the role of wingless-integrated/β-catenin (Wnt/β-catenin) …

It is unknown whether transplantation of bone marrow mesenchymal stem cells (BM-MSCs)
can repair spinal cord ischemia-reperfusion injury (SCII) in a rat model through an anti …

Objective Dexpanthenol (DXP) reportedly protects tissues against oxidative damage in
various inflammation models. This study aimed to evaluate its effects on oxidative stress …

The lung is severely affected by intestinal ischemia–reperfusion (I–R) injury. Mesna, a thiol
compound, possess anti-inflammatory and antioxidant properties. We aimed in the present …

Objective MicroRNA (miRNA) molecules are involved in the response of the central nervous
system to ischemia and reperfusion. We sought to test the hypothesis that overexpression of …

Objective Previous studies have shown niacin has neuroprotective effects on the central
nervous system. However, its specific effect on spinal cord ischemia/reperfusion injury has …

Background Darbepoetin-alpha (DA) is a novel erythropoiesis-stimulating agent developed
for treating anemia. In animal models, recombinant human erythropoietin has been reported …