Anxiety disorders are the most common class of mental illness in the US, affecting 40 million
individuals annually. Anxiety is an adaptive response to a stressful or unpredictable life …

Orchestrating appropriate behavioral responses in the face of competing signals that predict
either rewards or threats in the environment is crucial for survival. The basolateral nucleus of …

The processing of temporal intervals is essential to create causal maps and to predict future
events so as to best adapt one's behavior. In this review, we explore the different brain …

Conditioned fear requires neural activity in the basolateral amygdala (BLA) and medial
prefrontal cortex (mPFC), structures that are densely interconnected at the synaptic level …

Many lines of evidence suggest that a reciprocally interconnected network comprising the
amygdala, ventral hippocampus (vHC), and medial prefrontal cortex (mPFC) participates in …

When facing stress, most individuals are resilient whereas others are prone to developing
mood disorders. The brain mechanisms underlying such divergent behavioral responses …

Much is known about the neural circuits of conditioned fear and its relevance to
understanding anxiety disorders, but less is known about other anxiety-related behaviors …

Clinical studies have revealed that genetic variations in metabotropic glutamate receptor 3
(mGlu3) affect performance on cognitive tasks dependent upon the prefrontal cortex (PFC) …

Stressful life events are ubiquitous and well-known to negatively impact mental health.
However, in both humans and animal models, there is large individual variability in how …

Fear can potently inhibit ongoing behavior, including reward-seeking, yet the neural circuits
that underlie such suppression remain to be clarified. Prior studies have demonstrated that …