Short interspersed elements (SINEs) are one of the two most prolific mobile genomic
elements in most of the higher eukaryotes. Although their biology is still not thoroughly …

Retroelements comprise a considerable fraction of eukaryotic genomes. Since their initial
discovery by Barbara McClintock in maize DNA, retroelements have been found in genomes …

Our understanding of the development and maintenance of tissues has been greatly aided
by large-scale gene expression analysis. However, tissues are invariably complex, and …

Adenovirus is a common human pathogen that relies on host cell processes for transcription
and processing of viral RNA and protein production. Although adenoviral promoters, splice …

Short interspersed elements (SINEs) are mobile genetic elements that invade the genomes
of many eukaryotes. Since their discovery about 30 years ago, many gaps in our …

In eukaryotes, three RNA polymerases (Pol I, II, and III) are responsible for the transcription
of distinct subsets of genes. Gene-external type 3 Pol III promoters use defined transcription …

The recently discovered CRISPR/Cas9 system is widely-used in basic research and is a
useful tool for disease modeling and gene editing therapies. However, long-term expression …

RNA polymerase II (Pol II) is a well‐characterized DNA‐dependent RNA polymerase, which
has also been reported to have RNA‐dependent RNA polymerase (RdRP) activity. Natural …

Friedreich's ataxia (FRDA) is an untreatable disorder with neuro-and cardio-degenerative
progression. This monogenic disease is caused by the hyper-expansion of naturally …

International Review of Cell and Molecular Biology presents current advances and
comprehensive reviews in cell biology--both plant and animal. Articles address structure and …