Update from the 5th Edition of the World Health Organization classification of head and neck tumors: nasal cavity, paranasal sinuses and skull base

LDR Thompson, JA Bishop - Head and Neck Pathology, 2022 - Springer
Abstract The World Health Organization Classification of Head and Neck Tumours recently
published the 5th edition. There are new entities, emerging entities, and significant updates …

Sinonasal inverted papilloma and squamous cell carcinoma: contemporary management and patient outcomes

JG Eide, KC Welch, ND Adappa, JN Palmer, CCL Tong - Cancers, 2022 - mdpi.com
Simple Summary Inverted papillomas are benign sinonasal tumors that can recur or become
cancerous. The mainstay of treatment is surgical resection. We summarize the biology of …

DEK-AFF2 carcinoma of the sinonasal region and skull base: detailed clinicopathologic characterization of a distinctive entity

LM Rooper, A Agaimy, BC Dickson… - The American journal …, 2021 - journals.lww.com
Abstract A novel DEK-AFF2 fusion was recently reported in 4 nonkeratinizing squamous cell
carcinomas of the sinonasal region and skull base, including 1 with exceptional response to …

Untying the Gordian knot of composite hemangioendothelioma: Discovery of novel fusions

K Linos, JK Dermawan, M Pulitzer… - Genes …, 2024 - Wiley Online Library
Composite hemangioendothelioma is a rare, locally aggressive, and rarely metastasizing
vascular neoplasm which affects both children and adults. Recently, a number of gene …

Top ten oncocytic head and neck lesions to contemplate

MJ Bullock, XS Jiang - Head and Neck Pathology, 2023 - Springer
Background Oncocytes are a component of many metaplastic and neoplastic lesions
throughout the head and neck area, primarily originating in salivary/seromucinous glands …

Frequent EGFR exon 20 insertion in the so‐called peripheral‐type squamous cell neoplasm of uncertain malignant potential: a variant of bronchiolar adenoma or …

Q Zheng, L Hou, G Shang, X Qi, M Zhang, Y Jin… - …, 2023 - Wiley Online Library
Introduction Herein we describe a series of rare peripheral pulmonary neoplasms
temporarily termed “peripheral type squamous cell neoplasm of uncertain malignant …

Sinonasal papillomas: 10-year retrospective analysis of etiology, epidemiology, and recurrence

M Archang, L Chew, AYK Han… - American Journal of …, 2022 - journals.sagepub.com
Objectives To examine the epidemiology, subtypes, trends over time, and predictive factors
for recurrence and malignant transformation of sinonasal papillomas. Methods A …

EGFR Exon 20 Insertion Mutations in Sinonasal Squamous Cell Carcinoma

L Pacini, VN Cabal, MA Hermsen, PH Huang - Cancers, 2022 - mdpi.com
Simple Summary The majority of patients with sinonasal squamous cell carcinoma (SNSCC)
associated with inverted sinonasal papilloma carry an exon 20 insertion activating mutation …

Genomic sequencing of cancer-related genes in sinonasal squamous cell carcinoma and coexisting inverted papilloma

R Uchi, R Jiromaru, R Yasumatsu… - Anticancer …, 2021 - ar.iiarjournals.org
Background: The genetic basis of sinonasal inverted papilloma (SNIP)-derived squamous
cell carcinoma (SCC) has not yet been well characterized. Aim: To characterize the genetic …

[PDF][PDF] Loss of p16 expression is a risk factor for recurrence in sinonasal inverted papilloma

M Menendez del Castro, V Naves Cabal… - …, 2022 - digibuo.uniovi.es
Background: The purpose of this study was to evaluate p16, p53, EGFR, pEGFR protein
expression and HPV infection as possible markers of tumor progression in a series of …