Background & Aims The management of inflammatory bowel disease (IBD) poses a
particular challenge during pregnancy because the health of both the mother and the fetus …

Crohn's disease is a chronic inflammatory disease of the gastrointestinal tract, with
increasing incidence worldwide. Crohn's disease might result from a complex interplay …

A European League Against Rheumatism (EULAR) task force was established to define
points to consider on use of antirheumatic drugs before pregnancy, and during pregnancy …

In the United States, approximately 0.5% of the population, or 1.6 million people, have
inflammatory bowel disease (IBD)—Crohn's disease (CD) and ulcerative colitis (UC). 1, 2 Of …

Trying to conceive and being pregnant is an emotional period for those involved. In the
majority of patients suffering from inflammatory bowel disease, maintenance therapy is …

Background & Aims Little is known about in utero exposure to and postnatal clearance of
anti–tumor necrosis factor (anti-TNF) agents in neonates. We investigated the …

BACKGROUND & AIMS: Some women with inflammatory bowel disease require therapy
with tumor necrosis factor (TNF) antagonists during pregnancy. It is not clear whether these …

Tumor necrosis factor-α (TNF-α) is a central regulator of inflammation, and TNF-α
antagonists may be effective in treating inflammatory disorders in which TNF-α plays a major …

OBJECTIVES: Inflammatory bowel diseases (IBD) need long-term treatment, which can
influence pregnancies in young women. Uncontrolled IBD is associated with poor …

Background & Aims Biologics are used routinely in pregnant women with inflammatory
bowel disease (IBD), but large-scale data reporting adverse pregnancy outcomes among …