Because undesirable pharmacokinetics and toxicity are significant reasons for the failure of
drug development in the costly late stage, it has been widely recognized that drug ADMET …

Background Guttate psoriasis is common and affects 0.5–2% of individuals in the paediatric
age group. This review aims to familiarize physicians with the clinical manifestations …

Ebola and Dengue are the critical diseases caused by RNA viruses, especially in the
tropical parts of the globe, including Asia and Africa, and no prominent therapeutic options …

The drug efflux pump is a crucial mechanism implicated in resistance to multiple
antimicrobials. Thymoquinone (TQ) has evidently demonstrated multiple activities …

Chinese herbal medicine has recently gained worldwide attention. The curative mechanism
of Chinese herbal medicine is compared with that of western medicine at the molecular …

Plant extracts are gaining more attention as therapeutic agents against inflammation. In this
study, four different widely used herbals were selected, such as holy basil leaf, sesame …

Purpose The bioefficacy of accessible chemical structures has been established, leading to
some optimization to address these constraints. Methods This study aimed to identify the …

Clostridioides difficile is a pathogenic bacterium responsible for antibiotic-associated
diarrhea globally. The pathogenesis of this bacterium is due to its virulence toxins, which …

Objective: This article aimed to identify the bioactive compounds present in the brown algae
Sargassum tenerrimum using TLC and HPTLC fingerprinting analysis and followed in silico …

This study is aimed to determine the 3D structure of a bacterial virulence protein Sortase A
(SrtA) and to screen for curcumin analogues with high bioavailability and drug like …