In this article, we briefly review the identification of GHRH, provide an abridged overview of
GHRH antagonists, and focus on studies with GHRH agonists. Potent GHRH agonists of JI …

Thyroid-associated ophthalmopathy (TAO) is a vexing and poorly understood autoimmune
process involving the upper face and tissues surrounding the eyes. In TAO, the orbit can …

In concert with their phagocytic activity, macrophages are thought to regulate the host
immunometabolic responses primarily via their ability to produce specific cytokines and …

Dysregulation of Th17 cell differentiation and pathogenicity contributes to multiple
autoimmune and inflammatory diseases. Previously growth hormone releasing hormone …

The hallmarks of age-related immune senescence are chronic inflammation, aberrant
expansion of effector memory, and loss of naive T lymphocytes due in part to systemic …

Gastric cancer (GC) ranks as the fourth most frequent in incidence and second in mortality
among all cancers worldwide. The development of effective treatment approaches is an …

Growth hormone‐releasing hormone (GHRH) regulates the synthesis of growth hormone
from the anterior pituitary gland, and it is involved in inflammatory responses. On the other …

COVID-19 is characterized by an excessive inflammatory response and macrophage
hyperactivation, leading, in severe cases, to alveolar epithelial injury and acute respiratory …

Ocular inflammation is a major cause of visual impairment attributed to dysregulation of the
immune system. Previously, we have shown that the receptor for growth-hormone–releasing …

COVID-19 pneumonia causes acute lung injury and acute respiratory distress syndrome
(ALI/ARDS) characterized by early pulmonary endothelial and epithelial injuries with altered …