Reproduction of different tissues using scaffolds and materials is a major element in
regenerative medicine. The regeneration of whole organs with decellularized extracellular …

Biologic scaffolds composed of extracellular matrix (ECM) are widely used in both preclinical
animal studies and in many clinical applications to repair and reconstruct tissues. Recently …

Corneal blindness is one of the most common causes of vision loss worldwide, affecting
millions of people. To treat these patients, researchers have been examining different …

Biologic scaffold materials composed of mammalian extracellular matrix (ECM) are prepared
by decellularization of source tissues harvested from either humans (allogeneic) or a variety …

In view of their low immunogenicity, biomimetic internal environment, tissue-and organ-like
physicochemical properties, and functionalization potential, decellularized extracellular …

Tissue engineering is emerging as a possible alternative to methods aimed at alleviating the
growing demand for replacement tissues and organs. A major pillar of most tissue …

Biomaterials based on seeding of cells on decellularized scaffolds have gained increasing
interest in the last few years and suggested to serve as an alternative approach to …

To prepare acellular corneal scaffold, we used high-hydrostatic pressurization (HHP) to
decellularize porcine cornea. The HHP method disrupts cells by hydrostatic pressurization …

Corneal transplantation is an important surgical treatment for many common corneal
diseases. However, a worldwide shortage of tissue from suitable corneal donors has meant …

Background: Since the cornea is responsible for transmitting and focusing light into the eye,
injury or pathology affecting any layer of the cornea can cause a detrimental effect on visual …