Topical drug delivery: History, percutaneous absorption, and product development

MS Roberts, HS Cheruvu, SE Mangion… - Advanced drug delivery …, 2021 - Elsevier
Topical products, widely used to manage skin conditions, have evolved from simple potions
to sophisticated delivery systems. Their development has been facilitated by advances in …

New insights in topical drug delivery for skin disorders: from a nanotechnological perspective

N Raina, R Rani, VK Thakur, M Gupta - ACS omega, 2023 - ACS Publications
Skin, the largest organ in humans, is an efficient route for the delivery of drugs as it
circumvents several disadvantages of the oral and parenteral routes. These advantages of …

Dissecting the formation, structure and barrier function of the stratum corneum

T Matsui, M Amagai - International immunology, 2015 - academic.oup.com
The skin is the largest organ of the mammalian body. The outermost layer of mammalian
skin, the stratum corneum (SC) of the epidermis, consists of piles of dead corneocytes that …

Moisturization and skin barrier function

AV Rawlings, CR Harding - Dermatologic therapy, 2004 - Wiley Online Library
Over the past decade, great progress has been made toward elucidating the structure and
function of the stratum corneum (SC), the outermost layer of the epidermis. SC cells …

Solar UV radiation reduces the barrier function of human skin

K Biniek, K Levi, RH Dauskardt - Proceedings of the …, 2012 - National Acad Sciences
The ubiquitous presence of solar UV radiation in human life is essential for vitamin D
production but also leads to skin photoaging, damage, and malignancies. Photoaging and …

Structure and function of the epidermal barrier

RR Wickett, MO Visscher - American journal of infection control, 2006 - Elsevier
The skin is divided into 2 main structural layers: the epidermis and the dermis. The
epidermis is generally considered to be subdivided into 5 separate strata: basal, spinous …

The stratum corneum: structure and function in health and disease

CR Harding - Dermatologic therapy, 2004 - Wiley Online Library
Our understanding of the formation, structure, composition, and maturation of the stratum
corneum (SC) has progressed enormously over the past 30 years. Today, there is a growing …

Moisturizers: the slippery road

A Sethi, T Kaur, SK Malhotra… - Indian journal of …, 2016 - journals.lww.com
Moisturizers are an important part of a dermatologist's armamentarium although little is
written and well, a less is truly known about them. There is a cornucopia of projected skin …

[HTML][HTML] Stratum corneum moisturization at the molecular level: an update in relation to the dry skin cycle

AV Rawlings, PJ Matts - Journal of Investigative Dermatology, 2005 - Elsevier
'Stratum Corneum Moisturization At The Molecular Level'[1] was published over a decade
ago to review what was known about the biology of a common cosmetic problem called 'dry …

Corneocytes: relationship between structural and biomechanical properties

AS Évora, MJ Adams, SA Johnson… - Skin pharmacology and …, 2021 - karger.com
Background: Skin is the interface between an organism and the external environment, and
hence the stratum corneum (SC) is the first to withstand mechanical insults that, in certain …