Molecular mechanisms and physiological importance of circadian rhythms

A Patke, MW Young, S Axelrod - Nature reviews Molecular cell biology, 2020 - nature.com
To accommodate daily recurring environmental changes, animals show cyclic variations in
behaviour and physiology, which include prominent behavioural states such as sleep–wake …

Model and non-model insects in chronobiology

K Beer, C Helfrich-Förster - Frontiers in Behavioral Neuroscience, 2020 - frontiersin.org
The fruit fly Drosophila melanogaster is an established model organism in chronobiology,
because genetic manipulation and breeding in the laboratory are easy. The circadian clock …

Connectomic analysis of the Drosophila lateral neuron clock cells reveals the synaptic basis of functional pacemaker classes

OT Shafer, GJ Gutierrez, K Li, A Mildenhall, D Spira… - Elife, 2022 - elifesciences.org
The circadian clock orchestrates daily changes in physiology and behavior to ensure
internal temporal order and optimal timing across the day. In animals, a central brain clock …

Studying circadian rhythms in Drosophila melanogaster

O Tataroglu, P Emery - Methods, 2014 - Elsevier
Circadian rhythms have a profound influence on most bodily functions: from metabolism to
complex behaviors. They ensure that all these biological processes are optimized with the …

Temperature compensation and temperature sensation in the circadian clock

PB Kidd, MW Young, ED Siggia - Proceedings of the …, 2015 - National Acad Sciences
All known circadian clocks have an endogenous period that is remarkably insensitive to
temperature, a property known as temperature compensation, while at the same time being …

Molecular and circuit mechanisms mediating circadian clock output in the Drosophila brain

AN King, A Sehgal - European Journal of Neuroscience, 2020 - Wiley Online Library
A central question in the circadian biology field concerns the mechanisms that translate~ 24‐
hr oscillations of the molecular clock into overt rhythms. Drosophila melanogaster is a …

Reorganization of sleep by temperature in Drosophila requires light, the homeostat, and the circadian clock

KM Parisky, JLA Rivera, NC Donelson, S Kotecha… - Current Biology, 2016 - cell.com
Increasing ambient temperature reorganizes the Drosophila sleep pattern in a way similar to
the human response to heat, increasing daytime sleep while decreasing nighttime sleep …

Circadian rhythm of temperature preference and its neural control in Drosophila

H Kaneko, LM Head, J Ling, X Tang, Y Liu, PE Hardin… - Current Biology, 2012 - cell.com
A daily body temperature rhythm (BTR) is critical for the maintenance of homeostasis in
mammals. Whereas mammals use internal energy to regulate body temperature, ectotherms …

Crosstalk between the circatidal and circadian clocks mediates behavioral adaptation to tidal patterns

ER Kwiatkowski, JJC Rosenthal, P Emery - Current Biology, 2024 - cell.com
The ability to anticipate tides is critical for a wide range of marine organisms, but this task is
complicated by the diversity of tidal patterns on Earth. Previous findings suggest that …

Two clocks in the brain: an update of the morning and evening oscillator model in Drosophila

T Yoshii, D Rieger, C Helfrich-Förster - Progress in brain research, 2012 - Elsevier
Circadian clocks play an essential role in adapting the activity rhythms of animals to the day–
night cycles on earth throughout the four seasons. In many animals, including the fruit fly …