Whole-brain R1 predicts manganese exposure and biological effects in welders

DA Edmondson, CL Yeh, S Hélie, U Dydak - Archives of toxicology, 2020 - Springer
Manganese (Mn) is a neurotoxicant that, due to its paramagnetic property, also functions as
a magnetic resonance imaging (MRI) T1 contrast agent. Previous studies in Mn toxicity have …

Reversibility of neuroimaging markers influenced by lifetime occupational manganese exposure

DA Edmondson, RE Ma, CL Yeh, E Ward… - Toxicological …, 2019 - academic.oup.com
Manganese (Mn) is a neurotoxicant that many workers are exposed to daily. There is limited
knowledge about how changes in exposure levels impact measures in magnetic resonance …

[PDF][PDF] Sensitivity and Specificity of MRI Markers of Excess Manganese Brain Deposition

H Monsivais, G Francis, S Snyder, J Kuhn, U Dydak - researchgate.net
The pallidal index (PI) and the R1 relaxation rate are two commonly used MRI markers to
diagnose manganese (Mn) neurotoxicity caused by excess Mn accumulation in the brain …

Identifying Imaging Biomarkers for Manganese Toxicity in Occupationally Exposed Welders

DA Edmondson - 2019 - search.proquest.com
Manganese (Mn) is an essential element and, at high doses, a neurotoxin that many workers
are exposed to daily. Increased Mn body burden due to occupational exposures leads to a …