Abstract Background Structural variants (SVs) are chromosomal segments that differ
between genomes, such as deletions, duplications, insertions, inversions and …

Clinical mastitis (CM) is an inflammatory disease occurring in the mammary glands of
lactating cows. CM is under genetic control, and a prominent CM resistance QTL located on …

Pulmonary arterial hypertension (PAH) is a cardiovascular disease that has high incidence
and causes massive deaths. miR-155-5p/PYGL pathway was revealed to play a crucial role …

Milk yield is the most complex trait in dairy animals, and mapping all causal variants even
with smallest effect sizes has been difficult with the genome-wide association study (GWAS) …

Peripartum dairy cows commonly experience negative energy balance (EB) and
immunosuppression together with high incidences of infectious and metabolic disease. This …

At the individual cow level, suboptimum fertility, mastitis, negative energy balance, and
ketosis are major issues in dairy farming. These problems are widespread on dairy farms …

Simple Summary Conformation traits have been a key breeding goal in dairy cattle for many
years due to their relationship with animal productivity and other relevant characteristics …

We report the generation of an organism-wide catalog of 976,813 cis-acting regulatory
elements for the bovine detected by the assay for transposase accessible chromatin using …

Cows can live for over 20 years, but their productive lifespan averages only around 3 years
after first calving. Liver dysfunction can reduce lifespan by increasing the risk of metabolic …

Excessive negative energy balance in early lactation is linked to an increased disease risk
but may be mitigated by appropriate nutrition. The liver plays central roles in both …