Chemokines in the cancer microenvironment and their relevance in cancer immunotherapy
The tumour microenvironment is the primary location in which tumour cells and the host
immune system interact. Different immune cell subsets are recruited into the tumour …
immune system interact. Different immune cell subsets are recruited into the tumour …
The chemokine superfamily revisited
A Zlotnik, O Yoshie - Immunity, 2012 - cell.com
The chemokine superfamily consists of a large number of ligands and receptors. At first
glance, this family appears redundant and their ligand-receptor relationships promiscuous …
glance, this family appears redundant and their ligand-receptor relationships promiscuous …
Adipose tissue macrophage in obesity-associated metabolic diseases
Adipose tissue macrophage (ATM) has been appreciated for its critical contribution to
obesity-associated metabolic diseases in recent years. Here, we discuss the regulation of …
obesity-associated metabolic diseases in recent years. Here, we discuss the regulation of …
Molecular characterization of the tumor microenvironment in breast cancer
Here we describe the comprehensive gene expression profiles of each cell type composing
normal breast tissue and in situ and invasive breast carcinomas using serial analysis of …
normal breast tissue and in situ and invasive breast carcinomas using serial analysis of …
The role of CXC chemokines and their receptors in cancer
J Vandercappellen, J Van Damme, S Struyf - Cancer letters, 2008 - Elsevier
Chemokines, or chemotactic cytokines, and their receptors have been discovered as
essential and selective mediators in leukocyte migration to inflammatory sites and to …
essential and selective mediators in leukocyte migration to inflammatory sites and to …
Chemokines
KJ Laing, CJ Secombes - Developmental & Comparative Immunology, 2004 - Elsevier
Chemokines are small proteins that control cellular migration. An extensive family of these
molecules has been described in mammals containing nearly 50 members. Within this …
molecules has been described in mammals containing nearly 50 members. Within this …
CXC chemokines in cancer angiogenesis and metastases
The tumor microenvironment is extremely complex that depends on tumor cell interaction
with the responding host cells. Angiogenesis, or new blood vessel growth from preexisting …
with the responding host cells. Angiogenesis, or new blood vessel growth from preexisting …
A narrative review: CXC chemokines influence immune surveillance in obesity and obesity-related diseases: Type 2 diabetes and nonalcoholic fatty liver disease
Adipose tissue develops lipids, aberrant adipokines, chemokines, and pro-inflammatory
cytokines as a consequence of the low-grade systemic inflammation that characterizes …
cytokines as a consequence of the low-grade systemic inflammation that characterizes …
Chemokine function in periodontal disease and oral cavity cancer
SE Sahingur, WA Yeudall - Frontiers in immunology, 2015 - frontiersin.org
The chemotactic cytokines, or chemokines, comprise a superfamily of polypeptides with a
wide range of activities that include recruitment of immune cells to sites of infection and …
wide range of activities that include recruitment of immune cells to sites of infection and …
The multifarious roles of the chemokine CXCL14 in cancer progression and immune responses
JA Westrich, DW Vermeer, PL Colbert… - Molecular …, 2020 - Wiley Online Library
The chemokine CXCL14 is a highly conserved, homeostatic chemokine that is constitutively
expressed in skin epithelia. Responsible for immune cell recruitment and maturation, as well …
expressed in skin epithelia. Responsible for immune cell recruitment and maturation, as well …