An inclusive study of deleterious missense PAX9 variants using user-friendly tools reveals structural, functional alterations, as well as potential therapeutic targets.
Mutations in the PAX9 are responsible for non-syndromic tooth agenesis in humans,
although their structural and functional consequences on protein phenotype, stability, and …
although their structural and functional consequences on protein phenotype, stability, and …
The influence of new SARS-CoV-2 variant Omicron (B. 1.1. 529) on vaccine efficacy, its correlation to Delta variants: A computational approach
The newly discovered COVID variant B. 1.1. 529 in Botswana has more than 30 mutations in
spike and many other in non-spike proteins, far more than any other SARS-CoV-2 variant …
spike and many other in non-spike proteins, far more than any other SARS-CoV-2 variant …
Whole Exome Sequencing Uncovers Key Genetic Variants in Congenital Tooth Agenesis: An Integrative Omics Approach
This study investigates the genetic underpinnings of congenital tooth agenesis (CTA) using
a multiomics approach, integrating whole exome sequencing (WES) and RNA expression …
a multiomics approach, integrating whole exome sequencing (WES) and RNA expression …
In silico Study of the Uncertainly Significant VCP Variants reveal major Structural, Functional fluctuations leading to potential Disease-Based Associations
T Das, S Roychowdhury, P Das - bioRxiv, 2023 - biorxiv.org
Valosin containing protein is involved in a plethora of crucial functions from proteostasis,
stress granule clearance to genome maintenance and ubiquitination. Hence, mutations in …
stress granule clearance to genome maintenance and ubiquitination. Hence, mutations in …
Impact of B. 1.617 and RBD SARS-CoV-2 variants on vaccine efficacy: An in-silico approach
Purpose The existing panels of COVID-19 vaccines are based on the spike protein of an
earlier SARS-CoV-2 strain that emerged in Wuhan, China. However, the evolving nature of …
earlier SARS-CoV-2 strain that emerged in Wuhan, China. However, the evolving nature of …
Ectodermal dysplasia: A case report
V Revathy, P Chandran - Indian Journal of Case Reports, 2022 - mansapublishers.com
Ectodermal dysplasia (ED) is a rare group of inherited disorders with defects in the
development of one or more tissues derived from primary embryonic ectodermal derivatives …
development of one or more tissues derived from primary embryonic ectodermal derivatives …