Ghrelin, CCK, GLP-1, and PYY (3–36): secretory controls and physiological roles in eating and glycemia in health, obesity, and after RYGB

RE Steinert, C Feinle-Bisset, L Asarian… - Physiological …, 2017 - journals.physiology.org
The efficacy of Roux-en-Y gastric-bypass (RYGB) and other bariatric surgeries in the
management of obesity and type 2 diabetes mellitus and novel developments in …

Interoceptive regulation of skeletal tissue homeostasis and repair

Y Xiao, C Han, Y Wang, X Zhang, R Bao, Y Li, H Chen… - Bone Research, 2023 - nature.com
Recent studies have determined that the nervous system can sense and respond to signals
from skeletal tissue, a process known as skeletal interoception, which is crucial for …

Regulation of energy homeostasis by the NPY system

K Loh, H Herzog, YC Shi - Trends in Endocrinology & Metabolism, 2015 - cell.com
Obesity develops when energy intake exceeds energy expenditure over time. Numerous
neurotransmitters, hormones, and factors have been implicated to coordinately control …

Arcuate NPY controls sympathetic output and BAT function via a relay of tyrosine hydroxylase neurons in the PVN

YC Shi, J Lau, Z Lin, H Zhang, L Zhai, G Sperk… - Cell metabolism, 2013 - cell.com
Neuropepetide Y (NPY) is best known for its powerful stimulation of food intake and its
effects on reducing energy expenditure. However, the pathways involved and the regulatory …

Bone-to-brain: a round trip in the adaptation to mechanical stimuli

L Gerosa, G Lombardi - Frontiers in Physiology, 2021 - frontiersin.org
Besides the classical ones (support/protection, hematopoiesis, storage for calcium, and
phosphate) multiple roles emerged for bone tissue, definitively making it an organ …

[HTML][HTML] Factors affecting adipose tissue development in chickens: A review

G Wang, WK Kim, MA Cline, ER Gilbert - Poultry science, 2017 - Elsevier
The intense genetic selection for rapid growth in broilers has resulted in an increase in
voluntary feed intake and growth rate, accompanied by increased fat deposition in adipose …

Peripheral-specific Y1 receptor antagonism increases thermogenesis and protects against diet-induced obesity

C Yan, T Zeng, K Lee, M Nobis, K Loh, L Gou… - Nature …, 2021 - nature.com
Obesity is caused by an imbalance between food intake and energy expenditure (EE). Here
we identify a conserved pathway that links signalling through peripheral Y1 receptors (Y1R) …

Hypothalamus-adipose tissue crosstalk: neuropeptide Y and the regulation of energy metabolism

W Zhang, MA Cline, ER Gilbert - Nutrition & metabolism, 2014 - Springer
Neuropeptide Y (NPY) is an orexigenic neuropeptide that plays a role in regulating adiposity
by promoting energy storage in white adipose tissue and inhibiting brown adipose tissue …

The role of neuropeptide Y and peptide YY in the development of obesity via gut-brain axis

Y Wu, H He, Z Cheng, Y Bai… - Current Protein and …, 2019 - ingentaconnect.com
Obesity is one of the main challenges of public health in the 21st century. Obesity can
induce a series of chronic metabolic diseases, such as diabetes, dyslipidemia, hypertension …

[HTML][HTML] Diabesity and mood disorders: Multiple links through the microbiota-gut-brain axis

A Farzi, AM Hassan, G Zenz, P Holzer - Molecular aspects of medicine, 2019 - Elsevier
The global prevalence of diabesity is on the rise, and the clinical, social and economic
health burden arising from this epidemic is aggravated by a significant co-morbidity of …