The multifaced actions of curcumin in pregnancy outcome
G Tossetta, S Fantone, SR Giannubilo, D Marzioni - Antioxidants, 2021 - mdpi.com
Curcumin, also known as diferuloylmethane, is the main polyphenolic substance present in
the rhizomes of Curcuma longa L. This plant showed many beneficial effects and has been …
the rhizomes of Curcuma longa L. This plant showed many beneficial effects and has been …
HTRA family proteins in pregnancy outcome
S Fantone, SR Giannubilo, D Marzioni, G Tossetta - Tissue and Cell, 2021 - Elsevier
HTRA (High temperature requirement protease A) family proteins includes HTRA1 (L56 or
PRSS11), HTRA2/Omi, HTRA3 (PRSP) and HTRA4. These are oligomeric serine proteases …
PRSS11), HTRA2/Omi, HTRA3 (PRSP) and HTRA4. These are oligomeric serine proteases …
HtrA1 in Gestational Diabetes Mellitus: A Possible Biomarker?
G Tossetta, S Fantone, R Gesuita, GC Di Renzo… - Diagnostics, 2022 - mdpi.com
Background: The high-temperature requirement A 1 (HtrA1) is a multidomain secretory
protein with serine-protease activity, expressed in many tissues, including placenta, where …
protein with serine-protease activity, expressed in many tissues, including placenta, where …
Association between first trimester plasma htra1 level and subsequent preeclampsia: A possible early marker?
R Gesuita, C Licini, E Picchiassi, F Tarquini… - Pregnancy …, 2019 - Elsevier
Introduction Preeclampsia (PE) is associated with risk of maternal and fetal mortality and
morbidity. Several promising predictors of PE have been identified, but early pregnancy …
morbidity. Several promising predictors of PE have been identified, but early pregnancy …
HtrA1 in human urothelial bladder cancer: a secreted protein and a potential novel biomarker
T Lorenzi, M Lorenzi, E Altobelli… - … journal of cancer, 2013 - Wiley Online Library
Our aim was to analyze the expression of the serine protease HtrA1 in human bladder tissue
and urine in order to point out its possible association with the presence of urothelial bladder …
and urine in order to point out its possible association with the presence of urothelial bladder …
[HTML][HTML] Abnormal development of placenta in HtrA1-deficient mice
Abnormal levels of High temperature requirement A1 (HtrA1) protein have been repeatedly
observed in sera and placentas of preeclampsia patients. To understand the functions of …
observed in sera and placentas of preeclampsia patients. To understand the functions of …
[HTML][HTML] Low HtrA1 expression in patients with long‑standing ulcerative colitis and colorectal cancer
E Altobelli, G Latella, M Morroni… - Oncology …, 2017 - spandidos-publications.com
The association between inflammatory bowel disease (IBD) and colorectal cancer (CRC) is
being increasingly investigated. HtrA1 overexpression inhibits cell growth and proliferation …
being increasingly investigated. HtrA1 overexpression inhibits cell growth and proliferation …
Association of frailty with the serine protease HtrA1 in older adults
M Lorenzi, T Lorenzi, E Marzetti, F Landi… - Experimental …, 2016 - Elsevier
Frailty is a geriatric syndrome characterized by multi system dysregulation. It has been
suggested that chronic inflammation may be involved in the pathogenesis of frailty. No study …
suggested that chronic inflammation may be involved in the pathogenesis of frailty. No study …
Serum HtrA1 is differentially regulated between early-onset and late-onset preeclampsia
Introduction HtrA1 (high temperature requirement A1) is a serine protease of the HtrA family.
We have previously shown that the placenta expresses the highest level of HtrA1 mRNA …
We have previously shown that the placenta expresses the highest level of HtrA1 mRNA …
Co-expression network analysis and genetic algorithms for gene prioritization in preeclampsia
Background In this study, we explored the gene prioritization in preeclampsia, combining co-
expression network analysis and genetic algorithms optimization approaches. We analysed …
expression network analysis and genetic algorithms optimization approaches. We analysed …