NAFLD as a driver of chronic kidney disease

CD Byrne, G Targher - Journal of hepatology, 2020 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) and chronic kidney disease (CKD) are worldwide
public health problems, affecting up to 25–30%(NAFLD), and up to 10–15%(CKD) of the …

Non-alcoholic fatty liver disease and its relationship with cardiovascular disease and other extrahepatic diseases

LA Adams, QM Anstee, H Tilg, G Targher - Gut, 2017 - gut.bmj.com
Key physiological functions of the liver, including glucose and lipid metabolism, become
disturbed in the setting of non-alcoholic fatty liver disease (NAFLD) and may be associated …

Non-alcoholic fatty liver disease and risk of incident chronic kidney disease: an updated meta-analysis

A Mantovani, G Petracca, G Beatrice, A Csermely… - Gut, 2022 - gut.bmj.com
Objective Studies reported a significant association between non-alcoholic fatty liver
disease (NAFLD) and increased risk of chronic kidney disease (CKD). However, whether …

Long-term pioglitazone treatment for patients with nonalcoholic steatohepatitis and prediabetes or type 2 diabetes mellitus: a randomized trial

K Cusi, B Orsak, F Bril, R Lomonaco… - Annals of internal …, 2016 - acpjournals.org
Background: The metabolic defects of nonalcoholic steatohepatitis (NASH) and prediabetes
or type 2 diabetes mellitus (T2DM) seem to be specifically targeted by pioglitazone …

[HTML][HTML] NAFLD: a multisystem disease

CD Byrne, G Targher - Journal of hepatology, 2015 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease
in Western countries that is predicted to become also the most frequent indication for liver …

Nonalcoholic fatty liver disease and chronic vascular complications of diabetes mellitus

G Targher, A Lonardo, CD Byrne - Nature reviews endocrinology, 2018 - nature.com
Nonalcoholic fatty liver disease (NAFLD) and diabetes mellitus are common diseases that
often coexist and might act synergistically to increase the risk of hepatic and extra-hepatic …

Association of non-alcoholic fatty liver disease with chronic kidney disease: a systematic review and meta-analysis

G Musso, R Gambino, JH Tabibian, M Ekstedt… - PLoS …, 2014 - journals.plos.org
Background Chronic kidney disease (CKD) is a frequent, under-recognized condition and a
risk factor for renal failure and cardiovascular disease. Increasing evidence connects non …

Epidemiological modifiers of non-alcoholic fatty liver disease: Focus on high-risk groups

A Lonardo, S Bellentani, CK Argo, S Ballestri… - Digestive and Liver …, 2015 - Elsevier
An improved understanding of non-alcoholic fatty liver disease epidemiology would lead to
identification of individuals at high risk of developing chronic liver disease and extra-hepatic …

Nonalcoholic fatty liver disease increases risk of incident chronic kidney disease: a systematic review and meta-analysis

A Mantovani, G Zaza, CD Byrne, A Lonardo, G Zoppini… - Metabolism, 2018 - Elsevier
Background Recent studies examined the prognostic impact of nonalcoholic fatty liver
disease (NAFLD) on the risk of incident chronic kidney disease (CKD). However, the extent …

[PDF][PDF] Extrahepatic complications of nonalcoholic fatty liver disease

MJ Armstrong, LA Adams, A Canbay, WK Syn - Hepatology, 2014 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease, and is
strongly associated with the metabolic syndrome. In the last decade, it has become apparent …