Interactions of glial cells with neuronal synapses, from astrocytes to microglia and oligodendrocyte lineage cells
The mammalian brain is a complex organ comprising neurons, glia, and more than 1× 1014
synapses. Neurons are a heterogeneous group of electrically active cells, which form the …
synapses. Neurons are a heterogeneous group of electrically active cells, which form the …
Super-resolving microscopy in neuroscience
Fluorescence imaging techniques play a pivotal role in our understanding of the nervous
system. The emergence of various super-resolution microscopy methods and specialized …
system. The emergence of various super-resolution microscopy methods and specialized …
Light microscopy of proteins in their ultrastructural context
O M'Saad, J Bewersdorf - Nature communications, 2020 - nature.com
Resolving the distribution of specific proteins at the nanoscale in the ultrastructural context of
the cell is a major challenge in fluorescence microscopy. We report the discovery of a new …
the cell is a major challenge in fluorescence microscopy. We report the discovery of a new …
Purkinje cell microzones mediate distinct kinematics of a single movement
The classification of neuronal subpopulations has significantly advanced, yet its relevance
for behavior remains unclear. The highly organized flocculus of the cerebellum, known to …
for behavior remains unclear. The highly organized flocculus of the cerebellum, known to …
Multiplexed expansion revealing for imaging multiprotein nanostructures in healthy and diseased brain
Proteins work together in nanostructures in many physiological contexts and disease states.
We recently developed expansion revealing (ExR), which expands proteins away from each …
We recently developed expansion revealing (ExR), which expands proteins away from each …
Improved immunostaining of nanostructures and cells in human brain specimens through expansion-mediated protein decrowding
Proteins are densely packed in cells and tissues, where they form complex nanostructures.
Expansion microscopy (ExM) variants have been used to separate proteins from each other …
Expansion microscopy (ExM) variants have been used to separate proteins from each other …
3D molecular phenotyping of cleared human brain tissues with light-sheet fluorescence microscopy
The combination of optical tissue transparency with immunofluorescence allows the
molecular characterization of biological tissues in 3D. However, adult human organs are …
molecular characterization of biological tissues in 3D. However, adult human organs are …
Adsorptive capture of perrhenate (ReO4−) from simulated wastewater by cationic 2D-MOF BUC-17
Abstract Water-stable [Co 3 (tib) 2 (H 2 O) 12](SO 4) 3 (BUC-17) was hydrothermally
synthesized by adding formic acid as a modulator. The as-prepared BUC-17, whose zeta …
synthesized by adding formic acid as a modulator. The as-prepared BUC-17, whose zeta …
Adaptation of magnified analysis of the proteome for excitatory synaptic proteins in varied samples and evaluation of cell type-specific distributions
M Delhaye, J LeDue, K Robinson, Q Xu… - Journal of …, 2024 - Soc Neuroscience
Growing evidence suggests a remarkable diversity and complexity in the molecular
composition of synapses, forming the basis for the brain to execute complex behaviors …
composition of synapses, forming the basis for the brain to execute complex behaviors …
A survey of visualization and analysis in high‐resolution connectomics
The field of connectomics aims to reconstruct the wiring diagram of Neurons and synapses
to enable new insights into the workings of the brain. Reconstructing and analyzing the …
to enable new insights into the workings of the brain. Reconstructing and analyzing the …