Chromones as a privileged scaffold in drug discovery: A review

RS Keri, S Budagumpi, RK Pai… - European Journal of …, 2014 - Elsevier
The chromone and its derivatives are the most important heterocyclic compounds, which is a
common and integral feature of a variety of natural products and medicinal agents. These …

Health benefits of chromones: Common ingredients of our daily diet

RB Semwal, DK Semwal, S Combrinck… - Phytochemistry Reviews, 2020 - Springer
Chromones are naturally occurring phenolic compounds that are universally present in a
healthy human diet. To date, thousands of chromone derivatives, including chromone …

Omega-3 polyunsaturated lipophenols, how and why?

C Crauste, M Rosell, T Durand, J Vercauteren - Biochimie, 2016 - Elsevier
Polyphenols and n-3 polyunsaturated fatty acids (PUFAs) are two classes of natural
compounds, which have been highlighted in epidemiological studies for their health …

Stereoselective synthesis of protectin D1: a potent anti-inflammatory and proresolving lipid mediator

M Aursnes, JE Tungen, A Vik, J Dalli… - Organic & biomolecular …, 2014 - pubs.rsc.org
A convergent stereoselective synthesis of the potent anti-inflammatory, proresolving and
neuroprotective lipid mediator protectin D1 (2) has been achieved in 15% yield over eight …

Ag doped ZnO nanorods catalyzed photo-triggered synthesis of some novel (1H-tetrazol-5-yl)-coumarin hybrids

YA Attia, YMA Mohamed, MM Awad… - Journal of Organometallic …, 2020 - Elsevier
Herein, we reported a facile synthetic strategy for the synthesis of 1, 5-disubstituted tetrazole
(1, 5-DST) based chromone derivatives with different through photocatalyzed one-pot …

Advances in the site-selective C-5, C-3 and C-2 functionalization of chromones via sp 2 C–H activation

AT Benny, EK Radhakrishnan - RSC advances, 2022 - pubs.rsc.org
In this work, site-selective C–H activation at C-5, C-3 and C-2 positions of chromones for the
introduction of structural diversity to the chromone scaffold was studied. The keto group of …

Stereoselective synthesis of maresin 1

JE Tungen, M Aursnes, TV Hansen - Tetrahedron Letters, 2015 - Elsevier
Maresin 1 is a potent anti-inflammatory and pro-resolving lipid mediator derived from
docosahexaenoic acid. The total synthesis of maresin 1 is achieved in 10 steps and in 7 …

[HTML][HTML] In-vitro chemopreventive potential of a chromone from bomarea setacea (ALSTROEMERIACEAE) against colorectal cancer

A Herrera-R, G Moreno, P Araque… - Iranian Journal of …, 2021 - ncbi.nlm.nih.gov
Chemoprevention with natural products may provide important alternatives in the search for
new drugs to treat cancer. Thus, the ethanol extract of Bomarea setacea and its secondary …

Oxidative stress and neurodegenerative diseases: looking for a therapeutic solution inspired on benzopyran chemistry

A Gaspar, N Milhazes, L Santana… - Current topics in …, 2015 - ingentaconnect.com
Reactive species are continuously produced in vivo by all body tissues. However, when an
imbalance between the reactive species production and the endogenous pool of …

Comparison of food antioxidants and iron chelators in two cellular free radical assays: strong protection by luteolin

T Hofer, TØ Jørgensen, RL Olsen - Journal of agricultural and food …, 2014 - ACS Publications
Liver (HepG2) cells were incubated with 21 edible flavonoids, carotenoids, polyunsaturated
fatty acid (PUFA) chromones, and metal chelators for 1 h, washed in PBS, and challenged in …