[HTML][HTML] Platinum nanoparticles: the potential antioxidant in the human lung cancer cells

NAS Ismail, JX Lee, F Yusof - Antioxidants, 2022 - mdpi.com
Oxidative stress-related conditions associated with lung cells, specifically lung cancer, often
lead to a poor prognosis. We hypothesized that platinum nanoparticles (PtNPs) can play a …

In silico screening, synthesis, characterization and biological evaluation of novel anticancer agents as potential COX-2 inhibitors

A Sahu, D Pradhan, B Veer, S Kumar, R Singh… - DARU Journal of …, 2023 - Springer
Background Cyclooxygenase enzyme is frequently overexpressed in various types of cancer
and found to play a crucial role in poor prognosis in cancer patients. In current research, we …

[HTML][HTML] Diclofenac sensitizes signet ring cell gastric carcinoma cells to cisplatin by activating autophagy and inhibition of survival signal pathways

N Lae Lae Phoo, A Sukhamwang… - International Journal of …, 2022 - mdpi.com
Gastric cancer has one of the highest incidence rates of cancer worldwide while also
contributing to increased drug resistance among patients in clinical practice. Herein, we …

[HTML][HTML] Synthesis, Characterization and Biological Investigation of the Platinum (IV) Tolfenamato Prodrug–Resolving Cisplatin-Resistance in Ovarian Carcinoma Cell …

MC Barth, N Häfner, IB Runnebaum… - International journal of …, 2023 - mdpi.com
The research on the anticancer potential of platinum (IV) complexes represents one strategy
to circumvent the deficits of approved platinum (II) drugs. Regarding the role of inflammation …

Efficient microwave synthesis of flurbiprofen derivatives and their enhancement of efficacy in chronic inflammatory pain models and gastro-protective potential in post …

NZ Shah, A Khan, SA Halim, SK Avula… - Journal of …, 2024 - Taylor & Francis
Present research was designed to synthesize and characterize the flurbiprofen derivatives
and to evaluate their analgesic, anti-inflammatory and gastro-protective activities in post …

[HTML][HTML] The optimum inhibitory effects of Alpha Interferon and Cisplatin in colon cancer, a comparative in vitro study

A Muttar, I Ahmed, H Hameed - Journal of medicine and life, 2022 - ncbi.nlm.nih.gov
Cisplatin is well known as a potent anti-cancer agent against colon cancer. However, alpha
interferons are also widely used for cancer suppression. This in vitro study was designed to …

[PDF][PDF] Prodrug Approach: NSAID Conjugates of Platinum Compounds as Anti-Cancer Agents

B Nija - Iraqi Journal of Pharmaceutical Sciences (P-ISSN 1683 …, 2023 - iasj.net
Prodrug based synthetic approach is a very promising area of research to enhance the
pharmacokinetic and pharmacodynamic properties of the drugs with a remarkable reduction …

[PDF][PDF] From Pre-Protamine 2 to ICSI Success: A Comprehensive Analysis of Protamine Assembly and Fertility Outcome Prediction

T Abbas - researchgate.net
This study provides a comprehensive analysis of the role of Pre-Protamine 2 (Pre-P2) in
predicting Intra-Cytoplasmic Sperm Injection (ICSI) success through its influence on …