Streptococcus mutans: a new Gram-positive paradigm?
Despite the enormous contributions of the bacterial paradigms Escherichia coli and Bacillus
subtilis to basic and applied research, it is well known that no single organism can be a …
subtilis to basic and applied research, it is well known that no single organism can be a …
Protein secretion and surface display in Gram-positive bacteria
O Schneewind, DM Missiakas - … Transactions of the …, 2012 - royalsocietypublishing.org
The cell wall peptidoglycan of Gram-positive bacteria functions as a surface organelle for the
transport and assembly of proteins that interact with the environment, in particular, the …
transport and assembly of proteins that interact with the environment, in particular, the …
Streptococcus mutans extracellular DNA is upregulated during growth in biofilms, actively released via membrane vesicles, and influenced by components of the …
Streptococcus mutans, a major etiological agent of human dental caries, lives primarily on
the tooth surface in biofilms. Limited information is available concerning the extracellular …
the tooth surface in biofilms. Limited information is available concerning the extracellular …
[HTML][HTML] The sec translocase
DJF Du Plessis, N Nouwen, AJM Driessen - Biochimica et Biophysica Acta …, 2011 - Elsevier
The vast majority of proteins trafficking across or into the bacterial cytoplasmic membrane
occur via the translocon. The translocon consists of the SecYEG complex that forms an …
occur via the translocon. The translocon consists of the SecYEG complex that forms an …
The changing faces of Streptococcus antigen I/II polypeptide family adhesins
Streptococcus mutans antigen I/II (AgI/II) protein was one of the first cell wall‐anchored
adhesins identified in Gram‐positive bacteria. It mediates attachment of S. mutans to tooth …
adhesins identified in Gram‐positive bacteria. It mediates attachment of S. mutans to tooth …
[HTML][HTML] Co-translational membrane insertion of mitochondrially encoded proteins
M Ott, JM Herrmann - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2010 - Elsevier
The components of the mitochondrial proteome represent a mosaic of dual genetic origin:
while most mitochondrial proteins are encoded by nuclear genes and imported into the …
while most mitochondrial proteins are encoded by nuclear genes and imported into the …
YidC/Alb3/Oxa1 family of insertases
The YidC/Alb3/Oxa1 family functions in the insertion and folding of proteins in the bacterial
cytoplasmic membrane, the chloroplast thylakoid membrane, and the mitochondrial inner …
cytoplasmic membrane, the chloroplast thylakoid membrane, and the mitochondrial inner …
Co-translational protein targeting in bacteria
R Steinberg, L Knüpffer, A Origi, R Asti… - FEMS microbiology …, 2018 - academic.oup.com
About 30% of all bacterial proteins execute their function outside of the cytosol and have to
be transported into or across the cytoplasmic membrane. Bacteria use multiple protein …
be transported into or across the cytoplasmic membrane. Bacteria use multiple protein …
Targeting and insertion of membrane proteins
The insertion and assembly of proteins into the inner membrane of bacteria are crucial for
many cellular processes, including cellular respiration, signal transduction, and ion and pH …
many cellular processes, including cellular respiration, signal transduction, and ion and pH …
YidC occupies the lateral gate of the SecYEG translocon and is sequentially displaced by a nascent membrane protein
I Sachelaru, NA Petriman, R Kudva, P Kuhn… - Journal of Biological …, 2013 - ASBMB
Most membrane proteins are co-translationally inserted into the lipid bilayer via the
universally conserved SecY complex and they access the lipid phase presumably via a …
universally conserved SecY complex and they access the lipid phase presumably via a …