The present and future of whole genome sequencing (WGS) and whole metagenome sequencing (WMS) for surveillance of antimicrobial resistant microorganisms …

EA Oniciuc, E Likotrafiti, A Alvarez-Molina, M Prieto… - Genes, 2018 - mdpi.com
Antimicrobial resistance (AMR) surveillance is a critical step within risk assessment
schemes, as it is the basis for informing global strategies, monitoring the effectiveness of …

The Helicobacter pylori Genome Project: insights into H. pylori population structure from analysis of a worldwide collection of complete genomes

K Thorell, ZY Muñoz-Ramírez, D Wang… - Nature …, 2023 - nature.com
Helicobacter pylori, a dominant member of the gastric microbiota, shares co-evolutionary
history with humans. This has led to the development of genetically distinct H. pylori …

Role of restriction-modification systems in prokaryotic evolution and ecology

AS Ershova, IS Rusinov, SA Spirin, AS Karyagina… - Biochemistry …, 2015 - Springer
Restriction–modification (RM) systems are able to methylate or cleave DNA depending on
methylation status of their recognition site. It allows them to protect bacterial cells from …

Whole Genome Sequence and Phylogenetic Analysis Show Helicobacter pylori Strains from Latin America Have Followed a Unique Evolution Pathway

ZY Munoz-Ramirez, A Mendez-Tenorio… - Frontiers in cellular …, 2017 - frontiersin.org
Helicobacter pylori (HP) genetics may determine its clinical outcomes. Despite high
prevalence of HP infection in Latin America (LA), there have been no phylogenetic studies in …

A Survey of Helicobacter pylori Antibiotic-Resistant Genotypes and Strain Lineages by Whole-Genome Sequencing in China

Y Zhou, Z Zhong, S Hu, J Wang, Y Deng… - Antimicrobial agents …, 2022 - Am Soc Microbiol
Antibiotic resistance is the most important factor leading to failed Helicobacter pylori
eradication therapy, and personalized treatment based on antibiotic susceptibility is …

Helicobacter pylori infections in the Bronx, New York: surveying antibiotic susceptibility and strain lineage by whole-genome sequencing

R Saranathan, MH Levi, AR Wattam… - Journal of Clinical …, 2020 - Am Soc Microbiol
The emergence of drug resistance in Helicobacter pylori has resulted in a greater need for
susceptibility-guided treatment. While the alleles associated with resistance to clarithromycin …

Genetic diversity and virulence characteristics of Helicobacter pylori isolates in different human ethnic groups

A Hanafiah, BS Lopes - Infection, Genetics and Evolution, 2020 - Elsevier
Helicobacter pylori is the most predominant bacterium in almost 50% of the world's
population and colonization causes a persistent inflammatory response leading to chronic …

Helicobacter pylori virulence factors: relationship between genetic variability and phylogeographic origin

AM Rodriguez, DA Urrea, CF Prada - PeerJ, 2021 - peerj.com
Background Helicobacter pylori is a pathogenic bacteria that colonize the gastrointestinal
tract from human stomachs and causes diseases including gastritis, peptic ulcers, gastric …

Phylogenomics of Colombian Helicobacter pylori isolates

AJ Gutiérrez-Escobar, E Trujillo, O Acevedo, MM Bravo - Gut Pathogens, 2017 - Springer
Abstract Background During the Spanish colonisation of South America, African slaves and
Europeans arrived in the continent with their corresponding load of pathogens, including …

Shedding Light on the African Enigma: In Vitro Testing of Homo sapiens-Helicobacter pylori Coevolution

B Cavadas, M Leite, N Pedro, AC Magalhães, J Melo… - Microorganisms, 2021 - mdpi.com
The continuous characterization of genome-wide diversity in population and case–cohort
samples, allied to the development of new algorithms, are shedding light on host ancestry …