NMR and metabolomics—A roadmap for the future

DS Wishart, LL Cheng, V Copié, AS Edison… - Metabolites, 2022 - mdpi.com
Metabolomics investigates global metabolic alterations associated with chemical, biological,
physiological, or pathological processes. These metabolic changes are measured with …

A historical overview of natural products in drug discovery

DA Dias, S Urban, U Roessner - Metabolites, 2012 - mdpi.com
Historically, natural products have been used since ancient times and in folklore for the
treatment of many diseases and illnesses. Classical natural product chemistry …

Phenolic compounds: from plants to foods

V Cheynier - Phytochemistry reviews, 2012 - Springer
Phenolic compounds are a large class of plant secondary metabolites, showing a diversity of
structures, from rather simple structures, eg phenolic acids, through polyphenols such as …

The evolving role of natural products in drug discovery

FE Koehn, GT Carter - Nature reviews Drug discovery, 2005 - nature.com
Natural products and their derivatives have historically been invaluable as a source of
therapeutic agents. However, in the past decade, research into natural products in the …

Dereplication strategies in natural product research: How many tools and methodologies behind the same concept?

J Hubert, JM Nuzillard, JH Renault - Phytochemistry Reviews, 2017 - Springer
The development of new drugs will certainly benefit from an ever improving knowledge of
the living beings chemistry. However, identification of drugable molecules within the …

[图书][B] Flavonoids: chemistry, biochemistry and applications

OM Andersen, KR Markham - 2005 - taylorfrancis.com
Advances in the flavonoid field have been nothing short of spectacular over the last 20
years. While the medical field has noticed flavonoids for their potential antioxidant …

Review on a Traditional Herbal Medicine, Eurycoma longifolia Jack (Tongkat Ali): Its Traditional Uses, Chemistry, Evidence-Based Pharmacology and Toxicology

SU Rehman, K Choe, HH Yoo - Molecules, 2016 - mdpi.com
Eurycoma longifolia Jack (known as tongkat ali), a popular traditional herbal medicine, is a
flowering plant of the family Simaroubaceae, native to Indonesia, Malaysia, Vietnam and …

Untargeted large-scale plant metabolomics using liquid chromatography coupled to mass spectrometry

RCH De Vos, S Moco, A Lommen, JJB Keurentjes… - Nature protocols, 2007 - nature.com
Untargeted metabolomics aims to gather information on as many metabolites as possible in
biological systems by taking into account all information present in the data sets. Here we …

Dereplication: racing to speed up the natural products discovery process

SP Gaudêncio, F Pereira - Natural product reports, 2015 - pubs.rsc.org
Covering: 1993–2014 (July) To alleviate the dereplication holdup, which is a major
bottleneck in natural products discovery, scientists have been conducting their research …

Measuring the metabolome: current analytical technologies

WB Dunn, NJC Bailey, HE Johnson - Analyst, 2005 - pubs.rsc.org
The post-genomics era has brought with it ever increasing demands to observe and
characterise variation within biological systems. This variation has been studied at the …